Table 1 Demographic, metabolic and basic optical data of the participants

Age (year)

38.96 ± 14.61

43.60 ± 15.51

41.59 ± 9.37

2.558

0.079

Gender Female (n)

64

30

220

0.912

0.634

Male (n)

18

5

54

Duration of illness (year)

13.27 ± 11.44

8.43 ± 9.55

–

1.636

0.107

Smokers, n (%)

12 (14.6)

2 (5.7)

12 (4.4)

16.737

0.020

Positive family history, n (%)

24 (29.3)

2 (5.71)

3 (1.1)

32.715

< 0.001

BMI

24.68 ± 3.65

24.32 ± 4.86

23.94 ± 3.34

1.165

0.313

SBP^a (mmHg)

109.88 ± 8.39

108.86 ± 9.32

109.23 ± 9.22

0.213

0.808

DBP^b (mmHg)

71.28 ± 5.76

69.43 ± 5.39

70.69 ± 5.84

1.257

0.286

MAP^c (mmHg)

84.14 ± 6.19

82.57 ± 6.27

83.54 ± 6.38

0.778

0.460

ALT^d (U/L)

16.66 ± 13.33

33.26 ± 30.91

20.16 ± 15.14

10.423

< 0.001

AST^e (U/L)

18.52 ± 10.35

24.97 ± 11.44

19.31 ± 7.89

6.403

0.002

Glucose (mmol/L)

5.34 ± 2.70

4.67 ± 0.37

5.43 ± 1.51

2.240

0.108

Cholesterol (mmol/L)

4.24 ± 0.98

4.08 ± 0.74

4.77 ± 0.84

15.644

< 0.001

Triglyceride (mmol/L)

1.96 ± 1.22

1.64 ± 0.85

1.50 ± 1.24

3.857

0.022

UA^f (mol/L)

359.90 ± 72.50

279.90 ± 75.54

321.63 ± 83.80

11.548

< 0.001

Thyrotropin (mIU/L)

2.97 ± 2.43

2.29 ± 1.28

1.95 ± 0.81

1.585

0.212

TT3^g (nmol/L)

0.90 ± 0.21

0.81 ± 0.21

0.96 ± 0.18

2.078

0.133

FT3^h (pmol/L)

3.23 ± 0.66

3.19 ± 0.93

4.17 ± 1.49

5.685

0.005

TT4ⁱ (nmol/L)

12.76 ± 22.32

10.15 ± 15.61

7.64 ± 2.61

0.386

0.681

FT4^j (pmol/L)

1.50 ± 0.15

1.17 ± 1.97

0.83 ± 0.13

0.399

0.673

Eye pressure left (mmHg)

14.74 ± 3.22

13.97 ± 3.09

15.39 ± 2.70

4.303

0.014

Right (mmHg)

14.67 ± 3.53

14.30 ± 2.35

15.24 ± 2.51

2.419

0.091

Diopters (D) left eye (unnormal,n)

4.10 ± 1.74 (29)

2.60 ± 0.55 (5)

2.68 ± 1.18 (15)

5.322/12.00

0.008 (0.285)

right eye (unnormal,n)

4.12 ± 1.77 (29)

2.1 ± 0.52 (5)

2.71 ± 1.32 (15)

6.086/12.00

0.005 (0.285)

 Immediate memory

75.10 ± 20.49

72.52 ± 13.87

106.84 ± 10.51

151.15

< 0.001

 Visuospatial/Constructional

95.10 ± 14.81

95.92 ± 14.71

105.69 ± 14.91

14.08

< 0.001

 Language Index

90.91 ± 18.92

84.44 ± 14.78

106.82 ± 9.55

53.63

< 0.001

 Attention Index

97.07 ± 12.41

101.92 ± 11.08

120.04 ± 16.56

60.71

< 0.001

 Delayed Memory

86.10 ± 13.58

85.56 ± 16.65

111.14 ± 7.86

158.32

< 0.001

 Total Scale(t)

84.84 ± 13.78

83.24 ± 12.64

117.64 ± 12.13

198.91

< 0.001