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Table 1 Demographic, metabolic and basic optical data of the participants

From: Factors related to retinal nerve fiber layer thickness in bipolar disorder patients and major depression patients

Mean ± SD Bipolar disorder group Depression group Normal Control group t/F/χ2 P
Age (year) 38.96 ± 14.61 43.60 ± 15.51 41.59 ± 9.37 2.558 0.079
Gender Female (n) 64 30 220 0.912 0.634
Male (n) 18 5 54   
Duration of illness (year) 13.27 ± 11.44 8.43 ± 9.55 1.636 0.107
Smokers, n (%) 12 (14.6) 2 (5.7) 12 (4.4) 16.737 0.020
Positive family history, n (%) 24 (29.3) 2 (5.71) 3 (1.1) 32.715 < 0.001
BMI 24.68 ± 3.65 24.32 ± 4.86 23.94 ± 3.34 1.165 0.313
SBPa (mmHg) 109.88 ± 8.39 108.86 ± 9.32 109.23 ± 9.22 0.213 0.808
DBPb (mmHg) 71.28 ± 5.76 69.43 ± 5.39 70.69 ± 5.84 1.257 0.286
MAPc (mmHg) 84.14 ± 6.19 82.57 ± 6.27 83.54 ± 6.38 0.778 0.460
ALTd (U/L) 16.66 ± 13.33 33.26 ± 30.91 20.16 ± 15.14 10.423 < 0.001
ASTe (U/L) 18.52 ± 10.35 24.97 ± 11.44 19.31 ± 7.89 6.403 0.002
Glucose (mmol/L) 5.34 ± 2.70 4.67 ± 0.37 5.43 ± 1.51 2.240 0.108
Cholesterol (mmol/L) 4.24 ± 0.98 4.08 ± 0.74 4.77 ± 0.84 15.644 < 0.001
Triglyceride (mmol/L) 1.96 ± 1.22 1.64 ± 0.85 1.50 ± 1.24 3.857 0.022
UAf (mol/L) 359.90 ± 72.50 279.90 ± 75.54 321.63 ± 83.80 11.548 < 0.001
Thyrotropin (mIU/L) 2.97 ± 2.43 2.29 ± 1.28 1.95 ± 0.81 1.585 0.212
TT3g (nmol/L) 0.90 ± 0.21 0.81 ± 0.21 0.96 ± 0.18 2.078 0.133
FT3h (pmol/L) 3.23 ± 0.66 3.19 ± 0.93 4.17 ± 1.49 5.685 0.005
TT4i (nmol/L) 12.76 ± 22.32 10.15 ± 15.61 7.64 ± 2.61 0.386 0.681
FT4j (pmol/L) 1.50 ± 0.15 1.17 ± 1.97 0.83 ± 0.13 0.399 0.673
Eye pressure left (mmHg) 14.74 ± 3.22 13.97 ± 3.09 15.39 ± 2.70 4.303 0.014
Right (mmHg) 14.67 ± 3.53 14.30 ± 2.35 15.24 ± 2.51 2.419 0.091
Diopters (D) left eye (unnormal,n) 4.10 ± 1.74 (29) 2.60 ± 0.55 (5) 2.68 ± 1.18 (15) 5.322/12.00 0.008 (0.285)
right eye (unnormal,n) 4.12 ± 1.77 (29) 2.1 ± 0.52 (5) 2.71 ± 1.32 (15) 6.086/12.00 0.005 (0.285)
RBANS
 Immediate memory 75.10 ± 20.49 72.52 ± 13.87 106.84 ± 10.51 151.15 < 0.001
 Visuospatial/Constructional 95.10 ± 14.81 95.92 ± 14.71 105.69 ± 14.91 14.08 < 0.001
 Language Index 90.91 ± 18.92 84.44 ± 14.78 106.82 ± 9.55 53.63 < 0.001
 Attention Index 97.07 ± 12.41 101.92 ± 11.08 120.04 ± 16.56 60.71 < 0.001
 Delayed Memory 86.10 ± 13.58 85.56 ± 16.65 111.14 ± 7.86 158.32 < 0.001
 Total Scale(t) 84.84 ± 13.78 83.24 ± 12.64 117.64 ± 12.13 198.91 < 0.001
  1. aSystolicblood pressure
  2. bDiastolyc blood pressure
  3. cMean arterial pressure
  4. dAlanine aminotransferase
  5. eAspartate aminotransferase
  6. fUric acid
  7. gSerum total thyroid hormone 3
  8. hFree thyroid hormone 3
  9. iSerum total thyroid hormone 4
  10. jFree thyroid hormone 4