Fig. 6From: A Sequential Multiple Assignment Randomized Trial (SMART) study of medication and CBT sequencing in the treatment of pediatric anxiety disordersTests of Mediation. X = Treatment. M = Proposed Mediator. Y = 24-week outcomes. a = coefficient for correlation of X with M (M = aX). b = coefficient for correlation of M with Y (Y = bM). Y = c X = c’ + ab (the total effect of X on Y). M = a X (the effect of X on M). Y = c’ X + b M (direct effect of X on Y). a x b (mediation effect). Algebraic sign of a x b x c (type of mediation – complementary or suppressive)Back to article page