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Table 2 Antipsychotic prescription and their mean dose for patients age 10–12 years with early-onset schizophrenia

From: Gender differences in the use of atypical antipsychotics in early-onset schizophrenia: a nationwide population-based study in Brazil

Variables

Overall

N = 18,229

Male

N = 13,395

Female

N = 4834

P*

Atypical antipsychotic

Clozapine

  Dose (mg/day)&

150.82 ± 138.79

144.49 ± 138.15

165.13 ± 140.31

0.334

  Mean dose/DDD ratio

0.502 ± 0.46

0.481 ± 0.46

0.55 ± 0.46

 

Olanzapine

  Dose (mg/day)&

5.18 ± 15.1

5.43 ± 17.72

4.56 ± 3.82

0.261

  Mean dose /DDD ratio

0.512 ± 1.51

0.54 ± 1.77

0.45 ± 0.38

 

Risperidone

  Dose (mg/day)&

1.19 ± 2.11

1.19 ± 1.83

1.21 ± 2.79

0.501

  Mean dose /DDD ratio

0.24 ± 0.42

0.24 ± 0.36

0.24 ± 0.55

 

Quetiapine

  Dose (mg/day)&

81.22 ± 109.02

85.06 ± 116.13

74.37 ± 94.78

0.077

  Mean dose /DDD ratio

0.20 ± 0.27

0.21 ± 0.29

0.18 ± 0.23

 

Ziprasidone

  Dose (mg/day)&

43.43 ± 33.61

43.11 ± 33.36

43.94 ± 34.10

0.805

  Mean dose /DDD ratio

0.54 ± 0.42

0.53 ± 0.42

0.54 ± 0.42

 
  1. & t-test was performed to compare mean dose (mg/day) between male and female; * p-value refers to the difference between male and female