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Table 2 Causal effects of composite cognitive measure (COGNt), PANSS symptoms – sum (log(PANSSsumt)) and negative (log(PANSSnegt)) in separate models, on number of workinghours per week (WHt), by g-estimation in JUMP. Parameters refer to SNMM = (ψ0 + ψ1f(t))at (2), where at is COGNt, log(PANSSsumt), or log(PANSSnegt), and f(t) is the function in eq. (3) with λ = 0.8

From: G-estimation of causal pathways in vocational rehabilitation for adults with psychotic disorders – a secondary analysis of a randomized trial

  COGNt log (PANSSsumt) log (PANSSnegt)
  Estimate 95% CI p-value Estimate 95% CI p-value Estimate 95% CI p-value
ψ0 0.224 0.067, 0.381 0.005 1.55 −4.25, 7.35 0.6 3.59 −0.383, 7.564 0.077
ψ1 . . . −0.31 − 0.57, − 0.052 0.018 −0.288 − 0.476, − 0.099 0.0029