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Table 1 Comparison of socio-demographic and clinical data of psychiatric patients with and without APs

From: Off-label use of antipsychotic medications in psychiatric inpatients in China: a national real-world survey

  Total
(N = 981)
APs
(N = 620)
No APs (N = 361) Z/χ2 p
Male 392 (40.0%) 262 (42.3%) 130 (36.0%) 3.71 0.054
Age (years ± SD) 46.72 ± 19.97 46.02 ± 20.55 47.91 ± 18.89 −1.84 0.066
Marital status
 Married 625 (63.7%) 371 (59.8%) 254 (70.4%) 11.12 0.004
 Single 240 (24.5%) 166 (26.8%) 74 (20.5%)   
 Divorced/widowed 116 (11.8%) 83 (13.4%) 33 (9.1%)   
Education background
 Uneducated/primary/ middle school 499 (50.9%) 335 (54.0%) 164 (45.4%) 6.76 0.034
 Senior high/ vocational school 270 (27.5%) 160 (25.8%) 110 (30.5%)   
 College school or above 212 (21.6%) 125 (20.2%) 87 (24.1%)   
Medical insurance
 Employee medical insurance 391 (39.9%) 243 (39.2%) 148 (41.0%) 11.57 0.003
 Residents medical insurance 423 (43.1%) 288 (46.5%) 135 (37.4%)   
 Others 167 (17.0%) 89 (14.4%) 78 (21.6%)   
Duration of illness (years) 7.14 ± 9.13 7.22 ± 9.23 7.00 ± 8.98 −0.15 0.883
GAF scores at admission 52.57 ± 18.59 49.71 ± 18.55 57.48 ± 17.63 −6.96 < 0.001
First hospitalization (yes, %) 570 (58.1%) 341 (55.0%) 229 (63.4%) 6.67 0.010
Psychotic symptoms (yes,%) 337 (34.4%) 294 (47.4%) 43 (11.9%) 127.56 < 0.001
Involuntary admission 206 (21.0%) 169 (27.3%) 37 (10.2%) 39.79 < 0.001
Restrained during hospital (yes, %) 145 (14.8%) 128 (20.6%) 17 (4.7%) 46.00 < 0.001
Agitation (yes, %) 162 (16.5%) 138 (22.3%) 24 (6.6%) 40.32 < 0.001
Suicidality and self-injurious behavior (yes, %) 41 (4.2%) 31 (5.0%) 10 (2.8%) 2.83 0.092
Received ECT treatment (yes, %) 96 (9.8%) 67(10.8%) 29 (8.0%) 1.99 0.159
  1. APs antipsychotics, GAF global assessment function scale, ECT electroconvulsive therapy