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Table 4 Association between serum TBIL levels and cognitive function after PSM analysis

From: Sex differences between serum total bilirubin levels and cognition in patients with schizophrenia

 

male (n = 98)

female (n = 78)

 

Univariate Results

Multivariate

Results

Univariate

Results

Multivariate

Results

 

OR

(95%CI)

P value

OR (95%CI)

P value

OR

P value

OR

P value

Age (years)

1.010(0.976–1.045)

0.573

–

–

1.015(0.976–1.056)

0.460

–

–

BMI (kg/m2)

0.986(0.891–1.092)

0.790

–

–

0.981(0872–1.103)

0.745

–

–

Education (years)

0.939(0.825–1.070)

0.345

–

–

0.995(0.863–1.072)

0.942

–

–

Hypertension (yes/no)

NA

1

–

–

1.542(0.243–9.776)

0.646

–

–

Diabetes mellitus (yes/no)

1.533(0.245–9.600)

0.648

–

–

NA

1.000

–

–

Total disease duration (months)

1.001(0.998–1.004)

0.571

–

–

1.001(0.997–1.005)

0.552

–

–

Total PANSS score

1.001(0.981–1.021)

0.930

–

–

1.025(0.996–1.055)

0.086

1.025(0.996–1.055)

0.086

TBIL (μmol/L)

0.909 (0.841–0.983)

0.016*

0.909 (0.841–0.983)

0.016*

1.074(0.979–1.178)

0.133

NA

0.133

TC (mmol/L)

0.852(0.543–1.337)

0.486

–

–

0.920(0.618–1.368)

0.679

–

–

TG (mmol/L)

1.030(0.786–1.348)

0.831

–

–

0.951(0.813–1.113)

0.534

–

–

LDL (mmol/L)

0.767(0.466–1.260)

0.295

–

–

1.191(0.786–1.805)

0.410

–

–

HDL (mmol/L)

0.701(0.279–1.759)

0.449

–

–

1.123 (0.336–3.752)

0.851

–

–

Mean chlorpromazine equivalent (mg)

1.000(0.998–1.001)

0.589

  

1.000(0.999–1.002)

0.667

  
  1. Dependent variable: cognitive function (0 = normal, 1 = impairment). 95% CI 95% confidence interval. OR the odds ratio. *p < 0.05. PANSS Positive and negative syndrome scale. TBIL total bilirubin. TC total cholesterol. TG triglyceride. LDL low density lipoprotein. HDL high density lipoprotein