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Fig. 5 | BMC Psychiatry

Fig. 5

From: Aripiprazole lauroxil 2-month formulation with 1-day initiation in patients hospitalized for an acute exacerbation of schizophrenia: exploratory efficacy and patient-reported outcomes in the randomized controlled ALPINE study

Fig. 5

Change From Baseline in PANSS Subscale and CGI-S Scores With Paliperidone Palmitate, Observed Cases. A. PANSS Positive SubscaleaB. PANSS Negative Subscalec.

C. PANSS General Psychopathology Subscaled. D. CGI-Sa.

PANSS Positive subscale score calculated as sum of items P1–7 (Delusions, Conceptual disorganization, Hallucinatory behavior, Excitement, Grandiosity, Suspiciousness, Hostility); scoring range, 7–49b. Mean baseline score is indicated at the first timepoint; mean (SE) change from baseline scores are indicated at each subsequent timepointc. PANSS Negative subscale score calculated as sum of items N1–7 (Blunted affect, Emotional withdrawal, Poor rapport, Passive-apathetic social withdrawal, Difficulty in abstract thinking, Lack of spontaneity & flow of conversation, Stereotyped thinking); scoring range, 7–49d. PANSS General Psychopathology subscale score calculated as sum of items G1–16 (Somatic concern, Anxiety, Guilt feelings, Tension, Mannerisms & posturing, Depression, Motor retardation, Uncooperativeness, Unusual thought content, Disorientation, Poor attention, Lack of judgment & insight. Disturbance of volition, Poor impulse control, Preoccupation, Active social avoidance); scoring range, 16–112. BL, baseline; CGI-S, Clinical Global Impression−Severity; PANSS, Positive and Negative Syndrome Scale.

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