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Table 3 Psychiatric Behavior, Diagnosis, and Family History in relation to Reported SI History

From: Suicidality in individuals with Prader-Willi syndrome: a review of registry survey data

  Reported SI No Reported SI Total Count Pearson’s X2 (df),
p-value
Cramer’s V
Count (%) Count (%) Count (%)
Suicidal attempt Reported 25 (26.6) 0 (0) 25 (3.3) 180.484 (1), < 0.001 0.491
Not reported 69 (73.4) 656 (100) 725 (96.7)
Self-injurious behavior Yes 62 (66) 373 (56.9) 435 (58) 6.087 (2), 0.048 0.090
No 6 (6.4) 103 (15.7) 109 (14.5)
Unknown 26 (27.7) 180 (27.4) 206 (27.5)
Aggressive or Tantrum Behavior Yes 66 (70.2) 372 (56.7) 438 (58.4) 7.226 (2), 0.027  
No 2 (2.1) 44 (6.7) 46 (6.1) 0.098
Unknown 26 (27.7) 240 (36.6) 266 (35.5)  
Anxiety, Reported Yes 82 (87.2) 319 (48.6) 401 (53.5) 50.780 (2), < 0.001  
No 7 (7.4) 281 (42.8) 288 (38.4) 0.260
Unknown 5 (5.3) 56 (8.5) 61 (8.1)  
Anxiety, Confirmed Diagnosis Yes 60 (63.8) 188 (28.7) 248 (33.1) 45.953 (1), < 0.001 0.248
No/Unknown 34 (36.2) 468 (71.3) 502 (66.9)
Depression, Reported Yes 37 (39.4) 64 (9.8) 101 (13.5) 69.421 (2), < 0.001  
No 49 (52.1) 567 (86.4) 616 (82.1) 0.304
Unknown 8 (8.5) 25 (3.8) 33 (4.4)  
Depression, Confirmed Diagnosis Yes 42 (44.7) 57 (8.7) 99 (13.2) 92.958 (1), < 0.001 0.352
No/Unknown 52 (55.3) 599 (91.3) 651 (86.8)
Mania/Bipolar, Reported Yes 37 (39.4) 118 (18) 155 (20.7) 51.113 (2), < 0.001 0.261
No 46 (48.9) 524 (79.9) 570 (76)
Unknown 11 (11.7) 14 (2.1) 25 (3.3)
Mania/Bipolar, Confirmed Diagnosis Yes 21 (22.3) 31 (4.7) 52 (6.9) 39.536 (1), < 0.001 0.230
No/Unknown 73 (77.7) 625 (95.3) 698 (93.1)
Psychosis, Reported Yes 64 (68.1) 89 (13.6) 153 (20.4) 154.546 (2), < 0.001 0.454
No 22 (23.4) 514 (78.4) 536 (71.5)
Unknown 8 (8.5) 53 (8.1) 61 (8.1)
Psychosis, Confirmed Diagnosis Yes 25 (26.6) 37 (5.6) 62 (8.3) 47.611 (1), < 0.001 0.252
No/Unknown 69 (73.4) 619 (94.4) 688 (91.7)
First Degree Family Member with Psychiatric Diagnosis Yes 29 (30.9) 120 (18.3) 149 (19.9) 8.172 (2), 0.017 0.104
No 6 (6.4) 46 (7) 52 (6.9)
Unknown 59 (62.8) 490 (74.7) 549 (73.2)
  1. No Reported SI includes either “No” or “Don’t Know” responses; it does not include subjects who did not respond. Bold cells are those significant by post hoc test. NS: p-value greater than 0.05. Self-injurious behavior indicates presence or absence of common behaviors associated with PWS, such as skin picking, nail pulling, rectal digging, etc. Unknown includes both “Don’t know” and no answer. Diagnosis questions only asked if symptom question answered yes. Cramer’s V: Measure of Association (Effect size ranging 0 to 1)