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Table 2 Number and ratio, relative to sample size, of DSM-MDE, melancholic, and atypical symptoms, based on symptom endorsed in STAR*D (N=2496)

From: Heterogeneity in major depression and its melancholic and atypical specifiers: a secondary analysis of STAR*D

Symptoms

n

%

profiles

ratio

Sad mood

2332

93.43

1842

0.79

Lost interest

1982

79.41

1530

0.77

Lost pleasure a

1506

60.34

1154

0.77

Appetite/weight decreasea

1127

45.15

880

0.78

Appetite/weight increaseb

680

27.24

586

0.86

Insomnia

2274

91.11

1791

0.79

Hypersomniab

370

14.82

349

0.94

Psychomotor retardationa

231

9.25

219

0.95

Psychomotor agitationa

760

30.45

666

0.88

Fatigue

2009

80.49

1549

0.77

Worthlessness/guilt

1912

76.60

1482

0.78

Diminished concentration

2196

87.98

1712

0.78

Suicidality

494

19.79

447

0.91

Unreactive mood

1436

57.53

1096

0.76

Distinct quality of mood

1240

49.68

1018

0.82

Depression worse AMc

271

10.86

260

0.96

Early morning awakening

1243

49.80

945

0.76

Mood reactivity

1060

42.47

901

0.85

Leaden paralysis

806

32.29

633

0.79

Rejection sensitivity

1295

51.88

1003

0.78

  1. profiles = number of profiles of unique symptom profiles, ratio = ratio of unique profiles to patients (0 = maximum homogeneity, 1 = maximum heterogeneity, a also a symptom of the ‘melancholic features’ specifier, b also a feature of the ‘atypical features’ specifier. c AM = in the morning