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Table 1 Clinical characteristics of control group and MDD patients

From: Associations of serum cystatin C with depressive symptoms and suicidal ideation in major depressive disorder

Variable

MDD patients (n = 130)

Controls (n = 112)

Statistics

P

Age, year

30.00 (20.75–50.00)

31.00 (21.00–50.25)

Z = − 1.895

0.058

Gender, Male n (%)

49 (37.7%)

44 (39.3%)

 χ2 = 0.065

0.799

Smoking n (%)

17 (13.1%)

12 (10.7%)

 χ2 = 0.318

0.573

Alcohol consumption n (%)

7 (5.4%)

5 (4.5%)

 χ2 = 0.108

0.742

Family history of depression n (%)

15 (11.5%)

–

–

–

Traumatic life events n (%)

12 (9.2%)

–

–

–

HAMD-24 score

24.00 (22.00–28.00)

–

–

–

SSI scorea

8.00 (3.00–12.00)

–

–

–

Cys C (mg/L)

0.83 (0.75–0.93)

0.78 (0.73–0.85)

Z = − 3.314

0.001

Urea (mmol/L)

4.35 (3.57–5.29)

4.50 (3.73–5.38)

Z = − 0.849

0.396

Cr (μmol/L)

56.50 (50.00–67.00)

58.00 (47.25–70.00)

Z = − 0.171

0.865

UA (μmol/L)

306.50 (255.75–357.00)

301.00 (248.25–376.75)

Z = − 0.296

0.767

eGFR (mL/min/1.73m2)

110.84 (99.15–126.65)

115.76 (109.38–124.14)

Z = − 1.982

0.048

hs-CRP (mg/L)

0.14 (0.03–0.90)

0.11 (0.03–0.25)

Z = − 1.971

0.049

  1. All data are presented as the interquartile range (IQR). The independent t-test and Mann Whitney U test were used for comparison of continuous data, and chi-squared test was used for proportions
  2. a: the total SSI score; MDD: Major depressive disorder; HAMD-24: 24-item Hamilton Depression Scale; Cys C: serum Cystatin C; Cr: creatinine; UA: uric acid; hs-CRP: high-sensitivity C-reactive protein; eGFR: estimate glomerular filtration rate