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Table 2 Sensitivity, specificity, and positive and negative predictive values for a diagnosis MDD across various cutoffs of the PHQ-9 (n = 101)

From: Validity of the patient health questionnaire 9-item in autistic youths: a pilot study

Cutoff Score

Sensitivity (%)

Specificity (%)

Positive Predictive Value (%)

Negative Predictive Value (%)

Youden’s Index

Self-rated

 3

100.0

19.5

22.4

100.0

0.195

 4

100.0

25.6

23.8

100.0

0.256

 5

100.0

35.4

26.4

100.0

0.354

 6

89.5

37.8

25.0

93.9

0.273

 7

78.9

43.9

24.6

90.0

0.229

 8

78.9

50.0

26.8

91.1

0.289

 9

73.7

56.1

28.0

90.2

0.298

 10

68.4

58.5

27.7

88.9

0.270

 11

63.2

63.4

28.6

88.1

0.266

 12

63.2

70.7

33.3

89.2

0.339

 13

57.9

75.6

35.5

88.6

0.335

 14

47.4

79.3

34.6

86.7

0.266

 15

36.8

85.4

36.8

85.4

0.222

Parent-rated

 3

78.9

34.1

21.7

87.5

0.131

 4

78.9

40.2

23.4

89.2

0.192

 5

73.7

50.0

25.5

89.1

0.237

 6

73.7

58.5

29.2

90.6

0.322

 7

57.9

64.6

27.5

86.9

0.225

 8

47.4

73.2

29.0

85.7

0.205

 9

47.4

75.6

31.0

86.1

0.230

 10

42.1

78.0

30.8

85.3

0.202

 11

36.8

80.5

30.4

84.6

0.173

 12

31.6

84.1

31.6

84.1

0.157

  1. Grey: the proposed cutoff. Orange: the statistically optimal cutoff based on the Youden’s Index. Data contributed by author