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Table 2 Body Mass Index (BMI) and Physical Health Outcomes in Lithium Users and Non-Users with Bipolar Disorder (BD), n = 129

From: Obesity and metabolic comorbidity in bipolar disorder: do patients on lithium comprise a subgroup? A naturalistic study

Variable

Li Users (n = 66)

Non-Li Users (n = 63)

Stats

Obesity, [n(%)]

42.42% (n = 28)

34.92% (n = 22)

p = 0.384, x2 = 0.758

Mean BMI, (kg/m2) [mean (±SD)]

29.10 (+/−6.70)

30.20 (+/−8.57)

U = 2051, p = 0.895, z = −0.132

BMI stratification, [n (%)]

p = 0.184, x2 = 4.85

 Underweight, < 19

0% (n = 0)

0, 0

 

 Normal, 19–25

30.30% (n = 20,)

33.33%, (n = 21)

 Overweight, 25–30

27.27% (n = 18)

31.75%, (n = 20)

 Class I Obesity, 30–35

25.76%, (n = 17)

11.11%, (n = 7)

 Class II & III Obesity, >  35

16.67%, (n = 11)

23.81%, (n = 15)

Metabolic Syndrome [n (%)]

35.71% (n = 15)

44.18% (n = 19)

p = 0.623, x2 = 0.24

Waist circumference, NIH

 Male, [mean (±SD)]

107.91 (20.51)

107.77 (16.79)

U = 1906.5, p = 0.416, z = −0.813

 Female, [mean (±SD)]

98.85 (16.28)

105.97 (19.03)

Glucose Metabolism

 Fasting Blood Glucose (mmol/L), n = 107 [mean (±SD)]

5.52 (1.03)

6.10 (2.90)

U = 1344.5, p = 0.712, z = −0.369

 HbA1C (mmol/L), n = 95 [mean (±SD)]

5.24 (0.53)

6.01 (1.83)

U = 753.5, p = 0.006*, z = −2.76

 Diabetes, n = 87, [n (%)]

16.67% (n = 7)

33.33% (n = 15)

p = 0.088, x2 = 3.19

Lipid Profile

 Total Cholesterol (mmol/L), n = 103 [mean (±SD)]

4.72 (1.02)

4.92 (1.10)

U = 1233, p = 0.582, z = −0.55

  HDL (mmol/L), n = 102, [mean (±SD)]

1.30 (0.33)

1.24 (0.37)

U = 1084.5, p = 0.162, z = −1.40

  LDL (mmol/L), n = 100, [mean (±SD)]

2.79 (0.87)

2.75 (0.89)

U = 1110, p = 0.377, z = −0.883

 Triglycerides (mmol/L), n = 102, [mean (±SD)]

1.46 (0.88)

2.01 (1.25)

U = 947, p = 0.020*, z = −2.32

 Dyslipidemia, n = 96, [n (%)]

50%, (n = 23)

70%, (n = 35)

p = 0.06, x2 = 4.007

Hypertension

 Hypertension, n = 117, [n (%)]

12.96%, (n = 7)

19.05%, (n = 12)

p = 0.455, x2 = 0.791

Thyroid Function

 TSH, n = 103, [mean (±SD)]

2.39 (1.26)

2.60 (1.43)

U = 1187, p = 0.411, z = −0.823

 Hypothyroidism, n = 102, [n (%)]

41.81%, (n = 23)

59.57%, (n = 28)

p = 0.112, x2 = 3.196

  1. Complete information was available on all participants for BMI and waist circumference. For other domains, the number of patients available is indicated next to the name of each variable (n=).
  2. Abbreviations: Li Lithium, Stats Statistics, BMI Body mass index, HbA1c Hemoglobin A1c, HDL High-density lipoprotein, LDL Low-density lipoprotein, TSH Thyroid stimulating hormone
  3. * = statistical significance at two-tailed p < 0.05