Table 2 Depressive symptoms (PHQ-9) by the type of ovarian function suppression in patients with breast cancer
| Â | Ovarian Ablation (OA) n, (%) | Ovarian function suppression | ||
|---|---|---|---|---|
GnRH agonist (GnRHa) n, (%) | t or χ2 value | P value | ||
Total | 174 | 389 | Â | Â |
PHQ-9 scores Median(IQR) | 13 (8.0-17.0) | 11 (7.0-16.0) | Â | Â |
PHQ-9 scores Range | 1-24 | 0-25 | Â | Â |
PHQ-9 scores Mean (SD) | 12.8 ± 5.8 | 11.4 ± 5.7 | 1.892 | 0.059 |
PHQ-9 scores subgroups | ||||
 None or mild (0-7), n(%) | 40 (23.0) | 101 (26.0) |  |  |
 Moderate (8-14), n(%) | 63 (36.2) | 167 (42.9) |  |  |
 Major (15-19), n(%) | 49 (28.2) | 87 (22.4) |  |  |
 Severe (20-27), n(%) | 22 (12.6) | 34 (8.7) |  |  |
 Major Depression (PHQ≥15), n(%) | 71 (40.8) | 121 (31.1) | 5.033 | 0.025 |
 Suicidal ideation, n(%) | 15 (8.6) | 30 (7.7) | 0.135 | 0.713 |