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Table 3 Effect of maternal anxiety on birth weight

From: Maternal Anxiety and Infants Birthweight and Length of Gestation. A sibling design

 

Crude

Step1*

Step2**

Step3***

Beta [95% CI]

Beta [95% CI]

Beta [95% CI]

Beta [95% CI]

Full cohort

 No Anxiety

0 [Reference]

0 [Reference]

0 [Reference]

0 [Reference]

 Week 17

-56.5 [-78.8, -34.2]

-48.9 [-71.2, -26.6]

-22 [-43.7, -0.4]

-25.4 [-47.1, -3.8]

 Week 30

-83.1 [-106.7, -59.5]

-71.4 [-94.9, -47.8]

-44 [-66.7, -21.2]

-47.8 [-70.6, -25.1]

 Both

-116.6 [-146.3, -86.9]

-99.2 [-128.8, -69.5]

-58 [-86.8, -29.2]

-63.8 [-92.6, -35]

 Sample size

91,165

91,165

91,165

91,165

Sibling cohort

 No Anxiety

0 [Reference]

0 [Reference]

0 [Reference]

0 [Reference]

 Week 17

-34.8 [-58.9, -10.7]

-33.2 [-57.3, -9.1]

-4.5 [-27.4, 18.5]

-4.7 [-27.6, 18.3]

 Week 30

-57.5 [-88, -27]

-56.9 [-87.5, -26.3]

-27.7 [-56.9, 1.5]

-27.9 [-57.2, 1.3]

 Both

-139 [-184.5, -93.4]

-134.8 [-180.4, -89.2]

-33.5 [-77.8, 10.8]

-33.1 [-77.4, 11.2]

 Sample size1

12,480

12,480

12,480

12,480

  1. *Adjusted for smoking and alcohol intake.
  2. **Adjusted for smoking, alcohol intake, parity, birth complication, child’s sex and preeclampsia.
  3. ***Adjusted for smoking, alcohol intake, parity, birth complication, child’s sex, preeclampsia, maternal age, education and marital status.
  4. 1 Number of sibling “pairs”.