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Table 4 Effect of maternal anxiety on gestational age

From: Maternal Anxiety and Infants Birthweight and Length of Gestation. A sibling design

 

Crude

Step1*

Step2**

Step3***

Beta [95% CI]

Beta [95% CI]

Beta [95% CI]

Beta [95% CI]

Full cohort

 No Anxiety

0 [Reference]

0 [Reference]

0 [Reference]

0 [Reference]

 Week 17

-0.64 [-1.12, -0.16]

-0.61 [-1.09, -0.13]

-0.54 [-1.01, -0.07]

-0.44 [-0.91, 0.04]

 Week 30

-1.4 [-1.9, -0.89]

-1.35 [-1.86, -0.84]

-1.23 [-1.73, -0.74]

-1.14 [-1.64, -0.64]

 Both

-1.89 [-2.53, -1.25]

-1.82 [-2.46, -1.18]

-1.69 [-2.32, -1.06]

-1.52 [-2.15, -0.89]

 Sample size

91,165

91,165

91,165

91,165

Sibling cohort

 No Anxiety

0 [Reference]

0 [Reference]

0 [Reference]

0 [Reference]

 Week 17

0.35 [-0.21, 0.92]

0.35 [-0.21, 0.92]

0.37 [-0.19, 0.94]

0.36 [-0.2, 0.93]

 Week 30

-1.08 [-1.79, -0.37]

-1.08 [-1.8, -0.37]

-1.13 [-1.84, -0.42]

-1.11 [-1.82, -0.4]

 Both

-0.54 [-1.61, 0.52]

-0.54 [-1.61, 0.53]

-0.6 [-1.68, 0.47]

-0.54 [-1.62, 0.53]

 Sample size1

12,480

12,480

12,480

12,480

  1. *Adjusted for smoking and alcohol intake.
  2. **Adjusted for smoking, alcohol intake, parity, birth complication, child’s sex and preeclampsia.
  3. ***Adjusted for smoking, alcohol intake, parity, birth complication, child’s sex, preeclampsia, maternal age, education and marital status.
  4. 1Number of sibling “pairs”.