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Table 2 Comparison of Yale-Brown obsessive-compulsive scale (Y-BOCS) subscales score change from baseline for treatment groups

From: Memantine augmentation of sertraline in the treatment of symptoms and executive function among patients with obsessive-compulsive disorder: A double-blind placebo-controlled, randomized clinical trial

Y-BOCS subscale score reduction

Treatment group

memantine+sertraline

placebo+sertraline

Mean±SD

MD (95% CI)

p-Value

Mean±SD

MD (95% CI)

p-Value

Total

Week 4

23.03±6.42

4.85

(1.77-7.92)

<0.001

22.23±6.88

7.88

(4.48-11.27)

<0.001

Week 12

11.22±6.26

16.66

(13.62-19.69)

<0.001

9.5±6.34

20.61

(17.35-23.86)

<0.001

Obsession

Week 4

12.55±3.01

2.62

(1.20-4.03)

<0.001

11.73±3.67

3.80

(2.13-5.46)

<0.001

Week 12

6.29±3.33

8.88

(7.38-10.37)

<0.001

5.3±2.76

10.23

(8.82-11.63)

<0.001

Compulsion

Week 4

10.37±4.16

2.33(0.15-4.50)

0.03

10.42±4.15

4.15 (2.01–6.28)

<0.001

Week 12

4.90±3.42

7.80 (5.77–9.82)

<0.001

4.15±3.92

10.42 (8.34–12.49)

<0.001