Skip to main content

Table 2 Comparison of Yale-Brown obsessive-compulsive scale (Y-BOCS) subscales score change from baseline for treatment groups

From: Memantine augmentation of sertraline in the treatment of symptoms and executive function among patients with obsessive-compulsive disorder: A double-blind placebo-controlled, randomized clinical trial

Y-BOCS subscale score reduction Treatment group
memantine+sertraline placebo+sertraline
Mean±SD MD (95% CI) p-Value Mean±SD MD (95% CI) p-Value
Total Week 4 23.03±6.42 4.85
(1.77-7.92)
<0.001 22.23±6.88 7.88
(4.48-11.27)
<0.001
Week 12 11.22±6.26 16.66
(13.62-19.69)
<0.001 9.5±6.34 20.61
(17.35-23.86)
<0.001
Obsession Week 4 12.55±3.01 2.62
(1.20-4.03)
<0.001 11.73±3.67 3.80
(2.13-5.46)
<0.001
Week 12 6.29±3.33 8.88
(7.38-10.37)
<0.001 5.3±2.76 10.23
(8.82-11.63)
<0.001
Compulsion Week 4 10.37±4.16 2.33(0.15-4.50) 0.03 10.42±4.15 4.15 (2.01–6.28) <0.001
Week 12 4.90±3.42 7.80 (5.77–9.82) <0.001 4.15±3.92 10.42 (8.34–12.49) <0.001