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Table 2 Association between serum albumin level (g/dL) and PHQ-9 score

From: The association between serum albumin and depression in chronic liver disease may differ by liver histology

 

Unadjusted model

β (95% CI)

Model 1

β (95% CI)

Model 2

β (95% CI)

Albumin

-1.776 (-2.628, -0.924)

-1.374 (-2.281, -0.466)

-1.113 (-2.065, -0.162)

P-value

<0.0001

0.0031

0.0221

Albumin (quintile)

 Q1

Reference

Reference

Reference

 Q2

-0.812 (-1.957, 0.334)

-0.686 (-1.829, 0.457)

-0.960 (-2.084, 0.163)

 Q3

-0.534 (-1.634, 0.566)

-0.203 (-1.322, 0.915)

-0.441 (-1.551, 0.670)

 Q4

-1.659 (-2.687, -0.632)

-1.286 (-2.347, -0.226)

-1.281 (-2.353, -0.208)

 Q5

-1.834 (-2.854, -0.815)

-1.414 (-2.475, -0.354)

-1.462 (-2.564, -0.359)

P for trend

<0.001

0.003

0.009

  1. Unadjusted model: no covariates were adjusted
  2. Model 1: age, gender and race were adjusted
  3. Model 2: age, gender, race, body mass index, alcohol consumption, total bilirubin, alanine aminotransferase, aspartate aminotransferase, antidepressant use, controlled attenuation parameter and liver stiffness measurement were adjusted