Skip to main content
Fig. 2 | BMC Psychiatry

Fig. 2

From: Involvement of the long intergenic non-coding RNA LINC00461 in schizophrenia

Fig. 2

The expression level of LINC00461 in schizophrenia patients and regulated by rs410216 in the human hippocampus. A The LINC00461 mRNA level was decreased significantly in peripheral blood cells of first-onset schizophrenia (SZ) patients before and after 12-week treatment (SZ_12W) as compared with healthy controls (control n = 48, SZ n = 32, SZ_12W n = 32).***: P-value< 0.001 by Mann–Whitney u test. Data are presented as mean ± SEM. B rs410216 was significantly associated with the expression level of LINC00461 in the human hippocampus (P = 0.025). The individuals with AA genotype had lower LINC00461 expression level. C-F No evidence of association was observed between rs410216 with other nearby genes in 1 Mb genomic region, including TMEM161B, TMEM161B-AS1, MEF2C and MEF2C-AS1 (all P-value > 0.05). Data was retrieved from the GTEx. The Kruskal-Wallis test was used for the analysis

Back to article page