Table 1 Demographic and clinical characteristics at baseline by payer group and index antipsychotic weight gain risk profile

 Age (Mean, SD)

38.7 (18.2)

37.3 (18.1)*

41.9 (18.2)*

39.9 (13.8)

39.3 (14.0)*

41.1 (13.1)*

Gender (N, %)

 Male

1,627 (59.2%)

1,180 (61.0%)*

442 (55.4%)*

5,067(57.9%)

3,560 (59.3%)*

1,473 (55.3%)*

 Female

1,121 (40.8%)

754 (39.0%)*

356 (44.6%)*

3,681 (42.1%)

2,444 (40.7%)*

1,192 (44.7%)*

Race/ethnicity (N, %)^a

 White

-

-

-

2,150 (24.6%)

1,495 (24.9%)*

637 (23.9%)*

 Black

-

-

-

5,402 (61.8%)

3,652 (60.8%)*

1,699 (63.8%)*

 American Indian or Alaska Native

-

-

-

48 (0.5%)

30 (0.5%)*

17 (0.6%)*

 Hispanic

-

-

-

128 (1.5%)

87 (1.4%)*

39 (1.5%)*

 Asian or Pacific Islander

-

-

-

54 (0.6%)

36 (0.6%)*

18 (0.7%)*

 Other

-

-

-

24 (0.3%)

20 (0.3%)*

4 (0.2%)*

 Unknown/missing

-

-

-

942 (10.8%)

684 (11.4%)*

251 (9.4%)*

Schizophrenia subtype diagnoses (N, %)

 Paranoid schizophrenia

997 (36.3%)

674 (34.9%)*

316 (39.6%)*

3,657(41.8%)

2,475 (41.2%)*

1,165(43.7%)*

 Disorganized schizophrenia

62 (2.3%)

45 2.3%

17 2.1%

315(3.6%)

214(3.6%)

98(3.7%)

 Catatonic schizophrenia

45 (1.6%)

34 (1.8%)

9 (1.1%)

74 (0.9%)

54 (0.9%)

20 (0.8%)

 Other schizophrenia

1,066 (38.8%)

728 (37.6%)

332 (41.6%)

4,573 (52.3%)

3,153 (52.5%)

1,386 (52.0%)

 Schizoaffective disorder

365 (13.3%)

255 (13.2%)

106 (13.3%)

1,516 (17.3%)

1,043 (17.3%)

465(17.5%)

Other psychiatric conditions (N, %)

 Generalized anxiety disorder

176 (6.4%)

136 7.0%

40 5.0%

299 3.4%

206 (3.4%)

89(3.3%)

 Other anxiety disorder

511 (18.6%)

378 (19.5%)

132 (16.5%)

1,279 (14.6%)

918 (15.3%)*

337 (12.7%)*

 Major depressive disorder

589 (21.4%)

413 (21.4%)

172 (21.6%)

1,349 (15.4%)

984 (16.4%)*

355 (13.3%)*

 Other mood disorder

317 (11.5%)

229 (11.8%)

83 (10.4%)

884 (10.1%)

639 (10.6%)*

235 (8.8%)*

 Drug abuse

451 (16.4%)

364 (18.8%)*

87 (10.9%)*

1,820 (20.8%)

1,331 (22.2%)*

467 (17.5%)*

 Alcohol abuse

183 (6.7%)

143 7.4%

38 4.8%

1,099 (12.6%)

778 (13.0%)

308 (11.6%)

 Other substance abuse/dependency disorder

338 (12.3%)

247 (12.8%)

90 (11.3%)

2,771 (31.7%)

1,918 (32.0%)

818 (30.7%)

Cardiometabolic conditions (N, %)

 Weight gain/obesity

169 (6.2%)

108(5.6%)

60 (7.5%)

1,041 (11.9%)

673 (11.2%)*

350 (13.1%)*

 Dyslipidemia

443 (16.1%)

291 (15.1%)*

147 (18.4%)*

1,770 (20.2%)

1,159 (19.3%)*

591 (22.2%)*

 Pre-diabetes

66 (2.4%)

47 (2.4%)

19 (2.4%)

260 (3.0%)

175 (2.9%)

83 (3.1%)

 Type 2 diabetes mellitus

313 (11.4%)

194 (10.0%)*

114 (14.3%)*

1,386 (15.8%)

859 (14.3%)*

501 (18.8%)*

 Hypertension

671 (24.4%)

445 (23.0%)*

220 (27.6%)*

2,978 (34.0%)

1,971 (32.8%)*

960 (36.0%)*

 Cardiovascular disease/events

434 (15.8%)

297 (15.4%)

131 (16.4%)

1,192 (13.6%)

818 (13.6%)

351 (13.2%)

 Cerebrovascular disease/events

87 (3.2%)

52 (2.7%)*

33 (4.1%)*

310 (3.5%)

209 (3.5%)

92 (3.5%)

 Obstructive sleep apnea

102 (3.7%)

74 (3.8%)

27 (3.4%)

230 (2.6%)

140 (2.3%)*

82 (3.1%)*

Cardiometabolic-related medications (N, %)

 Antihypertensives

581 (21.1%)

381 (19.7%)*

197 (24.7%)*

2,328 (26.6%)

1,539 (25.6%)*

758 (28.4%)*

 Antidiabetic medications

226 (8.2%)

136 (7.0%)*

87 (10.9%)*

969 (11.1%)

584 (9.7%)*

366 (13.7%)*

 Lipid-lowering agents

434 (15.8%)

284 (14.7%)*

147 (18.4%)*

1,362 (15.6%)

907 (15.1%)

440 (16.5%)