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Table 3 Post-index cardiometabolic comorbidities by payer group and index antipsychotic weight gain risk profile

From: Cardiometabolic outcomes among schizophrenia patients using antipsychotics: the impact of high weight gain risk vs low weight gain risk treatment

 

Commercial Insurance

Medicaid

All Patients

HWGR

LWGR

All Patients

HWGR

LWGR

Cardiometabolic conditionsa, N (%)

 Weight gain/obesity

N = 2,579

N = 1,826

N = 738

N = 7,707

N = 5,331

N = 2,315

259 (10.0%)

168 (9.2%)*

88 (11.9%)*

1,078 (14.0%)

693 (13.0%)*

371 (16.0%)*

 Dyslipidemia

N = 2,305

N = 1,643

N = 651

N = 6,978

N = 4,845

N = 2,074

363 (15.7%)

251 (15.3%)

109 (16.7%)

1,253 (18.0%)

842 (17.4%)

398 (19.2%)

 Pre-diabetes

N = 2,682

N = 1,887

N = 779

N = 8,488

N = 5,829

N = 2,582

131 (4.9%)

89 (4.7%)

42 (5.4%)

464 (5.5%)

319 (5.5%)

138 (5.3%)

 Type 2 diabetes mellitus

N = 2,435

N = 1,740

N = 684

N = 7,362

N = 5,145

N = 2,164

116 (4.8%)

70 (4.0%)*

46 (6.7%)*

628 (8.5%)

423 (8.2%)

200 (9.2%)

 Hypertension

N = 2,077

N = 1,489

N = 578

N = 5,770

N = 4,033

N = 1,705

300 (14.4%)

210 (14.1%)

89 (15.4%)

1,266 (21.9%)

850 (21.1%)

404 (23.7%)

 Cardiovascular disease/events

N = 2,314

N = 1,637

N = 667

N = 7,556

N = 5,186

N = 2,314

365 (15.8%)

249 (15.2%)

115 (17.2%)

1,477 (19.5%)

1,012 (19.5%)

443 (19.1%)

 Cerebrovascular disease/events

N = 2,661

N = 1,882

N = 765

N = 8,438

N = 5,795

N = 2,573

82 (3.1%)

54 (2.9%)

27 (3.5%)

324 (3.8%)

210 (3.6%)

109 (4.2%)

 Obstructive sleep apnea

N = 2,646

N = 1,860

N = 771

N = 8,518

N = 5,864

N = 2,583

76 (2.9%)

38 (2.0%)*

37 (4.8%)*

254 (3.0%)

157 (2.7%)

89 (3.4%)

  1. *p < 0.05 between HWGR vs LWGR subgroups
  2. aConditions developed during the 24-months following index antipsychotic therapy (Denominators depict total number of patients with no evidence of specified diagnosis during 12-months prior to index date)
  3. Abbreviations: HWGR High weight gain risk index treatment regimen, LWGR Low weight gain risk index treatment regimen, N number