Fig. 1

Study Schema. aIncluded clozapine, iloperidone, and paliperidone (SZ only); olanzapine, risperidone, quetiapine (SZ or BD-I); and olanzapine/fluoxetine (BD-I only). bComorbidities were only assessed during the baseline and 12-month post-index periods. BD-I, bipolar I disorder; FGA, first-generation antipsychotic; SGA, second-generation antipsychotic; SZ, schizophrenia