Characteristics of platelet-associated parameters and their predictive values in Chinese patients with affective disorders

Table 4 Comparison of sociodemographic and laboratory variables among BD manic episodes, BD depressive episodes and healthy controls

Variables	BD depressive episodes group (n = 1664)	BD manic episodes group (n = 3444)	HC group (n = 6847)	F/²	P	P1	P2	P3	P4	P5	P6
Age(year)	39.35 ± 0.385^a	39.11 ± 0.260^a	42.82 ± 0.157	76.533	0.000	0.000	0.000	0.000	0.000	0.566	1.000
Sex (male/female)	836/828^a	1815/1629^a	2863/3984	122.471	0.000	0.000	0.000	0.000	0.000	0.099	0.297
Platelet	234.326 ± 1.544^a	238.354 ± 1.096^ab	252.994 ± 0.712	104.036	0.000	0.000	0.000	0.000	0.000	0.014	0.043
MPV	9.512 ± 0.027^a	9.650 ± 0.019^ab	8.699 ± 0.014	955.957	0.000	0.000	0.000	0.000	0.000	0.000	0.000
PDW	13.851 ± 0.058^a	13.863 ± 0.041^a	15.931 ± 0.019	1617.275	0.000	0.000	0.000	0.000	0.000	0.851	1.000
PCT	0.206 ± 0.001^a	0.214 ± 0.001^ab	0.218 ± 0.001	37.358	0.000	0.000	0.001	0.000	0.001	0.000	0.002
Neutrophil	3.670 ± 0.039	3.962 ± 0.031^ab	3.597 ± 0.014	59.877	0.000	0.250	0.751	0.000	0.000	0.000	0.000
Lymphocyte	1.986 ± 0.016	2.012 ± 0.011	1.963 ± 0.007	0.865	0.421	0.590	1.000	0.311	0.934	0.225	0.676
RDW	13.557 ± 0.038^a	13.474 ± 0.027^a	13.272 ± 0.014	58.631	0.000	0.000	0.000	0.000	0.000	0.059	0.177
Albumin	43.642 ± 0.100^a	43.303 ± 0.068^ab	45.999 ± 0.033	1293.414	0.000	0.000	0.000	0.000	0.000	0.000	0.000
PLR	128.612 ± 1.269^a	130.729 ± 0.965^a	136.981 ± 0.545	13.316	0.038	0.000	0.000	0.001	0.002	0.075	0.226
SII	489.108 ± 9.022	530.295 ± 7.122^ab	492.205 ± 2.910	21.994	0.000	0.859	1.000	0.000	0.000	0.000	0.000
RPR	0.062 ± 0.001^a	0.061 ± 0.000^ab	0.056 ± 0.000	99.604	0.000	0.000	0.000	0.000	0.000	0.011	0.033
PAR	5.394 ± 0.036	5.530 ± 0.026^b	5.520 ± 0.016	6.756	0.001	0.019	0.058	0.035	0.105	0.000	0.000

HC Healthy controls, BD Bipolar disorder, MPV Mean platelet volume, PDW Platelet distribution width, PCT Plateletcrit, RDW Red blood cell distribution width, PLR Platelet to lymphocyte ratio, SII Systemic immune-inflammation index, RPR RDW to platelet ratio, PAR Platelet to albumin ratio; a, vs. HC group, P < 0.05; b, vs. BD depressive episodes, P < 0.05, p values after correction. P, comparison among BD depressive episodes group, BD manic episodes group and HC group; P1, BD depressive episodes group vs HC group, p values uncorrected; P2, BD depressive episodes group vs HC group, p values after correction; P3, BD manic episodes group vs HC group, p values uncorrected; P4, BD manic episodes group vs HC group, p values after correction; P5, BD depressive episodes group vs BD manic episodes group, p values uncorrected; P6, BD depressive episodes group vs BD manic episodes group, p values after correction. Values are represented as mean ± SEM

ISSN: 1471-244X