Fig. 6

Voxel-to-voxel connectivity in healthy controls (HCs) and patients with major depressive disorder (MDD). The whole-brain voxel-based connectivity revealed reduced connectivity of neural networks during the cognitive reappraisal task (contrast between ‘reappraise vs. view’). The significant threshold was p < .005 uncorrected voxel level and with p < .05 FWE-correction at the cluster level. HCs showed a wide-spread neural network distribution of voxel-to-voxel connectivity during the task. In contrast, patients with MDD showed less pattern of activation during the task. No clusters in the post-traumatic stress disorder group survived correction