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Table 2 Seed-to-voxel connectivity for right IFG (pars triangularis + opercularis) seed during cognitive reappraisal (reappraise > view). Threshold was p < .005 voxel-level and FWE-cluster correction p < .05

From: Transdiagnostic alterations in neural emotion regulation circuits – neural substrates of cognitive reappraisal in patients with depression and post-traumatic stress disorder

 

Peak MNI coordinates [mm]

Extent [voxel]

Peak t-values

x

y

z

 Brain regions

PTSD > HC 

  Frontal orbital cortex (l)

−42

24

−12

529

−5.49

  Temporal pole (l)

     

  Inferior frontal gyrus (l)

     

  Frontal operculum (l)

     

  Insular cortex (l)

     

 PTSD > MDD

  Precuneus

−06

−38

42

1338

6.53

  Posterior cingulate gyrus

     

  Paracingulate gyrus (b)

00

48

18

634

4.23

  Anterior cingulate gyrus

     

  Superior frontal gyrus (b)

     

  Frontal orbital cortex (l)

−46

24

−16

414

5.32

  Temporal pole (l)

     

 HC > MDD

  none of the voxels

     

  survived correction