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Table 4 Results of univariate Cox regression analysis for the rehospitalization of patients in a psychiatric hospital, followed-up from 2012 to 2017. Brasília, Brazil

From: Risk factors associated with readmissions of patients with severe mental disorders under treatment with antipsychotics

Factor

β

Relative Risk

(95% CI)

P-value

Marital status

 With partner

0.00

1.00 [Reference]

NA

 No partner

0.10

1.10 (0.92–1.33)

0.295

Sex

 Female

0.00

1.00 [Reference]

NA

 Male

0.10

1.11 (0.95–1.29)

0.208

Housing circumstances

 Lives with family members

0.00

1.00 [Reference]

NA

 Lives alone

0.06

1.06 (0.72–1.55)

0.768

 Lives in a public hostel

0.01

1.01 (0.61–1.65)

0.997

 Homeless

0.00

1.11 (0.73–1.68)

0.624

 Others Type

-0.59

0.56 (0.18–1.73)

0.310

Tobacco/Alcohol use

 Both

0.00

1.00 [Reference]

NA

 Tobacco use

-0.12

0.89 (0.72–1.09)

0.264

 Alcohol use

-0.25

0.78 (0.59–1.03)

0.083

 None

-0.36

0.70 (0.58–0.85)

 < 0.001

Cannabis/Cocaine use

 Cannabis

0.00

1.00 [Reference]

NA

 Cocaine

0.07

1.07 (0.72–1.60)

0.724

 Both

0.11

1.12 (0.81–1.55)

0.486

 None

-0.32

0.72 (0.54–0.97)

0.032

Presence of lifetime suicide attempt

 No

0.00

1.00 [Reference]

NA

 Yes

0.18

1.20 (0.96–1.50)

0.107

Adherence to Treatment

 Yes

0.00

1.00 [Reference]

NA

 No

0.71

2.03 (1.79–2.39)

 < 0.001

Treatment interruption due to lack of medication in public pharmacies

 Yes

0.00

1.00 [Reference]

NA

 No

-0.31

0.73 (0.58–0.92)

0.006

Replacement of antipsychotic due to lack of therapeutic response

 No

0.00

1.00 [Reference]

NA

 Yes

0.06

1.07 (0.84–1.35)

0.598

Change of antipsychotic due to ADRs ª

 No

0.00

1.00 [Reference]

NA

 Yes

0.09

1.09 (0.81–1.46)

0.558

Antipsychotic group used

 Atypical

0.00

1.00 [Reference]

NA

 Typical

0.31

1.37 (1.16–1.69)

0.001

Antipsychotic used

 Aripiprazole

  No

0.00

1.00 [Reference]

NA

  Yes

-0.35

0.70 (0.26–1.88)

0.481

 Chlorpromazine

  No

0.00

1.00 [Reference]

NA

  Yes

0.09

1.09 (0.81–1.47)

0.575

 Clozapine

  No

0.00

1.00 [Reference]

NA

  Yes

-0.07

0.93 (0.54–1.61)

0.793

 Haloperidol

  No

0.00

1.00 [Reference]

NA

  Yes

0.20

1.22 (1.03–1.44)

0.021

 Levomepromazine

  No

0.00

1.00 [Reference]

NA

  Yes

0.33

1.39 (0.82–2.36)

0.225

 Olanzapine

  No

0.00

1.00 [Reference]

NA

  Yes

-0.25

0.78 (0.49–1.24)

0.289

 Quetiapine

  No

0.00

1.00 [Reference]

NA

  Yes

-0.26

0.77 (0.54–1.12)

0.171

 Risperidone

  No

0.00

1.00 [Reference]

NA

  Yes

-0.29

0.75 (0.58–0.96)

0.024

 Thioridazine

  No

0.00

1.00 [Reference]

NA

  Yes

-0.12

1.12 (0.42–3.00)

0.817

  1. β Regression coefficient
  2. 95% CI 95% Confidence Interval
  3. aAdverse Drug Reactions