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Table 2 Brain areas with significantly different FC among the SD, NSD, and HC groups using the left vAI as the seed region

From: Aberrant functional connectivity in insular subregions in somatic depression: a resting-state fMRI study

Brain regions MNI (x y z) Cluster size F/t -value
Three groups
 Rectus_L -6 48–18 9 11.258a
 Rectus_R 9 45–18 11 11.135a
 Fusiform_R 24–30 -18 10 12.893a
 Inferior frontal orbital gyrus_R 48 39–6 23 11.666a
 Angular_R 63–51 27 9 8.885a
SD vs NSD
 Rectus_R 9 45–18 10 −4.513b
 Fusiform_R 24–30 -18 10 -5.146b
 Angular_R 60–51 24 9 -4.341b
SD vs HC
 Fusiform_R 24–30 -21 4 -4.493b
NSD vs HC
 Rectus_L −6 48–18 6 4.002b
 Rectus_R 3 42–21 9 4.227b
 Inferior frontal orbital gyrus_R 48 39–9 20 4.575b
  1. SD Somatic depression, NSD Non-somatic depression, HC Healthy control, vAI ventral anterior insula, MNI Montreal Neurological Institute, x, y, z are the coordinates of the primary peak locations in the MNI space; F is obtained by one-way analysis of variance; t is obtained by two-sample two-tailed t test (p < 0.05, alphasim correction), L Left, R Right
  2. aThe F statistical value
  3. bThe t statistical value