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Table 3 Brain areas with significantly different FC among the SD, NSD, and HC groups using the right vAI as the seed region

From: Aberrant functional connectivity in insular subregions in somatic depression: a resting-state fMRI study

Brain regions

MNI (x y z)

Cluster size

F/t -value

Three groups

 Superior frontal orbital gyrus_R

15 36–21

6

9.581a

 Inferior frontal orbital gyrus_L

−36 18–18

7

9.403a

 Superior frontal gyrus_R

21 27 54

7

8.568a

 Middle cingulate gyrus_R

9–39 33

20

11.745a

 Posterior cingulate gyrus_L

−6 − 42 24

7

11.388a

 Precuneus_R

9–63 24

9

9.456a

SD vs NSD

 Middle cingulate gyrus_R

9–39 33

16

−4.657b

 Precuneus_R

9–63 24

9

− 4.483b

 Superior frontal gyrus_R

21 27 54

7

-4.190b

SD vs HC

 Posterior cingulate gyrus_L

−6 − 42 24

7

−4.717b

 Precuneus_R

12–39 39

16

-4.722b

NSD vs HC

 Superior frontal orbital gyrus_R

18 36–21

6

3.852b

 Inferior frontal orbital gyrus_L

−33 21–18

3

3.588b

  1. SD Somatic depression, NSD Non-somatic depression, HC Healthy control, vAI Ventral anterior insula, MNI Montreal Neurological Institute, x, y, z are the coordinates of the primary peak locations in the MNI space; F is obtained by one-way analysis of variance; t is obtained by two-sample two-tailed t test (p < 0.05, alphasim correction); L left, R Right
  2. aThe F statistical value
  3. bThe t statistical value