Aberrant functional connectivity in insular subregions in somatic depression: a resting-state fMRI study

BMC Psychiatry

Table 5 Brain areas with significantly different FC among the SD, NSD, and HC groups using the right dAI as the seed region

Brain regions	MNI (x y z)	Cluster size	F/t -value
Three groups
Fusiform_R	33–3 -30	8	15.960^a
Postcentral_L	−33–33 60	19	12.451^a
SD vs NSD
Postcentral_L	−33–30 63	17	−5.457^b
SD vs HC
Fusiform_R	33–3 -30	8	−5.433^b
Postcentral_L	−36 − 33 57	7	−3.807^b
NSD vs HC
Fusiform_R	30–3 -33	3	-3.669^b

SD Somatic depression, NSD Non-somatic depression, HC Healthy control, dAI Dorsal anterior insula, MNI Montreal Neurological Institute, x, y, z are the coordinates of the primary peak locations in the MNI space; F is obtained by one-way analysis of variance; t is obtained by two-sample two-tailed t test (p < 0.05, alphasim correction); L left, R Right
^aThe F statistical value
^bThe t statistical value

ISSN: 1471-244X