Table 5 Comparison of clinical features and symptoms severity in patients with different genotypes of rs12294045

Gender

Male(110)

Female(123)

53 (0.48)

64 (0.52)

9 (0.08)

11 (0.09)

48 (0.44)

48 (0.39)

0.510

0.775

Age of onset

(years, Χ ± S)

24.06 ± 7.77

26.70 ± 7.14

23.99 ± 6.90

1.205

0.302

Onset form

Acute(22)

Subacute(28)

Chronic(183)

10 (0.46)

14 (0.50)

93 (0.51)

4 (0.18)

0 (0)

16 (0.09)

8 (0.36)

14 (0.50)

74 (0.40)

5.560

0.235

Duration

(months, Χ ± S)

97.94 ± 96.04

109.00 ± 105.4

99.56 ± 96.45

0.111

0.895

Family history

Positive(162)

Negative(71)

73 (0.45)

44 (0.62)

14 (0.09)

6 (0.08)

75 (0.46)

21 (0.30)

6.162

0.046

Interpersonal relationship

Good(15)

General(123)

Poor(95)

8 (0.53)

67 (0.54)

42 (0.44)

2 (0.13)

11 (0.09)

7 (0.08)

5 (0.34)

45 (0.37)

46 (0.48)

3.794

0.435

Premorbid character

Extro(37)

Neutral(14)

Intro(182)

20 (0.54)

7 (0.50)

90 (0.49)

2 (0.05)

1 (0.07)

17 (0.09)

15 (0.41)

6 (0.43)

75 (0.41)

0.734

0.947

Marital status

Unmarried(116)

Married(75)

Living apart(10)Divorced(28)

Loss of spouse(4)

59 (0.51)

39 (0.52)

5 (0.50)

14 (0.50)

0 (0)

8 (0.07)

6 (0.08)

3 (0.30)

2 (0.07)

1 (0.25)

49 (0.42)

30 (0.40)

2 (0.20)

12 (0.43)

3 (0.75)

11.423

0.179

State of occupation

Full-time(64)

Part-time(38)

Jobless*(93)

Unemployment*(9)

Retired(28)

Other works(1)

32 (0.50)

19 (0.50)

43 (0.46)

7 (0.78)

15 (0.54)

1 (1)

5 (0.08)

3 (0.08)

9 (0.10)

0 (0)

3 (0.10)

0 (0)

27 (0.42)

16 (0.42)

41 (0.44)

2 (0.22)

10 (0.36)

0 (0)

5.027

0.889

PANSS(Χ ± S)

Positive score

27.74 ± 4.17

28.05 ± 4.05

28.52 ± 5.40

1.299

0.541

PANSS(Χ ± S)

Negative score

23.72 ± 5.45

24.10 ± 4.52

23.80 ± 5.11

0.046

0.955

PANSS(Χ ± S)

psychopathology

47.74 ± 7.02

49.80 ± 7.75

48.44 ± 7.12

0.798

0.452

PANSS(Χ ± S)

Total score

99.20 ± 11.46

101.95 ± 10.43

100.76 ± 11.35

0.801

0.450