Blood biomarkers of post-stroke depression after minor stroke at three months in males and females

Qiu, Xiuli; Wang, He; Lan, Yan; Miao, Jinfeng; Pan, Chensheng; Sun, Wenzhe; Li, Guo; Wang, Yanyan; Zhao, Xin; Zhu, Zhou; Zhu, Suiqiang

doi:10.1186/s12888-022-03805-6

BMC Psychiatry

Table 4 The multiple comparisons of exercise habit, fibrinogen and FT4 in male

From: Blood biomarkers of post-stroke depression after minor stroke at three months in males and females

Variables	Model 1				Model 2				Model 3
Variables	β	p	OR	95%CI	β	p	OR	95%CI	β	p	OR	95%CI
Exercise habit	-0.817	0.002	0.442	0.266–0.734	-	-	-	-	-	-	-	-
Fibrinogen	-	-	-	-	0.324	0.011	1.383	1.076–1.777	-	-	-	-
FT4	-	-	-	-	-	-	-		0.042	0.051	1.043	1.006–1.082
Age	0.010	0.382	1.010	0.988–1.033	0.002	0.868	1.002	0.980–1.024	0.006	0.599	1.006	0.984–1.028
Stroke type	0.580	0.161	1.786	0.794–4.017	0.525	0.204	1.690	0.753–3.795	0.711	0.087	2.036	0.902–4.595
Education level
Low		Rf	Rf	Rf		Rf	Rf	Rf		Rf	Rf	Rf
Medium	-0.342	0.253	0.710	0.394–1.28	-0.388	0.196	0.679	0.377–1.221	-0.390	0.190	0.677	0.378–1.214
High	-0.578	0.131	0.561	0.265–1.187	-0.723	0.055	0.485	0.232–1.014	-0.773	0.040	0.462	0.220–0.967
Smoking history	-0.291	0.288	0.748	0.438–1.278	-0.381	0.161	0.683	0.401–1.163	-0.343	0.206	0.710	0.417–1.208
Diabetes Mellitus	0.882	0.010	2.416	1.234–4.729	0.767	0.024	2.153	1.108–4.184	0.815	0.016	2.260	1.166–4.377
Hyperlipidemia	-0.492	0.118	0.611	0.329–1.134	-0.595	0.061	0.551	0.296–1.027	-0.512	0.105	0.600	0.323–1.112
Stroke history	-0.450	0.146	0.638	0.348–1.169	-0.406	0.188	0.666	0.364–1.219	-0.377	0.220	0.686	0.376–1.253
Direct bilirubin	0.109	0.149	1.115	0.962–1.292	0.089	0.236	1.093	0.943–1.266	0.078	0.296	1.081	0.934–1.251
Indirect bilirubin	-0.064	0.035	0.938	0.883–0.996	-0.049	0.104	0.952	0.898–1.010	-0.062	0.042	0.940	0.886–0.998
Triglyceride	-0.078	0.375	0.925	0.777–1.100	-0.024	0.782	0.976	0.822–1.158	-0.054	0.546	0.947	0.794–1.130
Potassium	-0.364	0.306	0.695	0.346–1.395	-0.378	0.284	0.685	0.343–1.368	-0.361	0.310	0.697	0.347–1.399
Sodium	0.071	0.253	1.073	0.951–1.212	-0.085	0.160	1.089	0.967–1.227	0.090	0.147	1.094	0.969–1.235
Chlorine	-0.061	0.201	0.941	0.856–1.033	-0.053	0.259	0.948	0.864–1.040	-0.061	0.204	0.941	0.857–1.033
Calcium	-1.162	0.319	0.313	0.032–3.076	-1.110	0.336	0.330	0.034–3.167	-1.142	0.314	0.319	0.035–2.947
Phosphorus	0.792	0.252	2.208	0.570–8.553	0.724	0.291	2.063	0.538–7.916	0.898	0.187	2.455	0.646–9.333
Magnesium	-0.262	0.862	0.770	0.040–14.763	-0.216	0.886	0.806	0.043–15.290	0.141	0.924	1.151	0.063–21.116
CRP	-0.006	0.406	0.994	0.981–1.008	-0.010	0.198	0.990	0.975–1.005	-0.003	0.690	0.997	0.984–1.001
D-dimer	0.060	0.378	1.062	0.929–1.215	0.071	0.309	1.074	0.936–1.231	0.065	0.342	1.067	0.933–1.220
HbA1C	-0.169	0.105	0.844	0.688–1.036	-0.195	0.062	0.823	0.671–1.010	-0.184	0.076	0.832	0.679–1.020
Testosterone	-0.006	0.930	0.994	0.869–1.137	-0.003	0.961	0.997	0.871–1.140	-0.003	0.960	0.997	0.871–1.140
Interleukin 6	-0.001	0.822	0.999	0.995–1.004	0.001	0.899	1.001	0.994–1.005	-0.001	0.770	0.999	0.995–1.004
TNF-α	-0.03	0.080	0.997	0.993–1.000	-0.003	0.072	0.997	0.993–1.000	-0.003	0.074	0.997	0.993–1.000
Interferon-γ	0.001	0.866	1.000	0.997–1.003	0.001	0.594	1.001	0.998–1.004	0.001	0.524	1.001	0.998–1.004
Fasting C peptide	0.143	0.091	1.154	0.978–1.363	0.110	0.193	1.116	0.946–1.317	0.114	0.169	1.121	0.953–1.318
Cortisol	0.019	0.473	1.019	0.967–1.075	0.004	0.883	1.004	0.953–1.058	0.016	0.547	1.016	0.965–1.070
ACTH	0.002	0.636	1.002	0.993–1.012	0.002	0.715	1.002	0.992–1.011	0.001	0.837	1.001	0.991–1.082

CRP hypersensitive C-reactive protein, FT4 free tetraiodothyronine, HbA1C glycosylated hemoglobin, TNF-α tumor necrosis factor-α, ACTH brain-derived neurotrophic factor

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