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Table 3 Sociodemographic and Health-related Characteristics of Participants in the Four Loneliness and Isolated Living Status Groups

From: Loneliness and isolated living status in middle-aged and older adults in Taiwan: exploration on stress-related biomarkers, depressive symptoms, and disability

 

aNeither Lonely, nor Isolated (N=438)

bNot Lonely,

but Isolated

(N=100)

cLonely,

but Not Isolated

(N=49)

dLonely and Isolated

(N=42)

F or χ2

Pairwise comparisons

among means

Age

65.0±7.2

69.2±7.0

66.2±7.1

69.1±6.8

12.2***

a<b, a<d

Sex

    

30.5***

 

 Male

287(65.5)

39(39)

27(55.1)

17(40.5)

  

 Female

151(34.5)

61(61)

22(44.9)

25(59.5)

  

Education

    

20.8

 

 No schooling

97(22.2)

29(29)

20(40.8)

16(38.1)

  

 Elementary (<6 years)

195(44.5)

46(46)

17(34.7)

20(47.6)

  

 Junior High (7-9 years)

53(12.1)

10(10)

2(4.1)

3(7.1)

  

 Senior High (9-12 years)

50(11.4)

11(11)

6(12.2)

2(4.8)

  

 College (>12 years)

43(9.8)

4(4)

4(8.2)

1(2.4)

  

Comorbidity+

0.8±0.9

0.9±1.0

1.1±1.1

1.2±1.2

4.3***

a<d

Loneliness2006

 Yes

43(9.8)

17(17.0)

10(20.4)

17(40.5)

  

 No

395(90.2)

83(83.0)

39(79.6)

25(59.5)

  

Isolated living status2006

 Yes

39(8.9)

99(99.0)

10(20.4)

41(97.6)

  

 No

399(91.1)

1(1.0)

39(79.6)

1(2.4)

  

Perceived Stress Scale

8.6±5.9

8.6±6.9

13.4±7.1

11.5±7.7

9.1***

b<c, d<c

Stress-related Biomarkers

 Cortisol levels2000

21.2±20.4

16.6±13.3

18.3±10.6

12.7±7.9

4.2**

a>d

 Cortisol levels2006

11.9±15.7

9.2±13.2

21.1±26.7

10.1±23.6

4.2**

a<c, b<c

 IL-6 levels2000

2.9±3.3

2.9±2.4

2.7±2.7

3.7±4.7

0.8

 

 IL-6 levels2006

3.7±5.3

3.9±4.3

6.6±11.2

5.1±7.4

3.5*

a<c

 hsCRP2000

-

-

-

-

-

-

 hsCRP2006

0.3±0.5

0.3±0.5

0.8±1.6

0.3±0.3

7.67***

a<c, b<c, d<c

Depression#

  CES-D2000

3.8±4.0

4.3±3.8

10.5±6.1

9.2±6.0

51.4***

a<c, a<d, b<c, b<d

  CES-D2006

4.3±4.7

5.4±5.5

6.6±5.4

8.5±7.1

11.0***

a<c<d, b<d

Disability

 Mobility2000

2.0±3.4

3.7±4.3

5.3±6.0

5.3±5.5

20.3***

a<b, a<c<d

 Mobility2006

4.3±5.6

6.7±6.7

6.3±7.0

8.3±7.3

9.6***

a<b, a<d

 IADLs2000

0.4±1.5

1.0±2.1

1.5±2.6

1.4±2.1

10.8***

a<b, a<c, a<d

 IADLs2006

1.6±3.2

2.9±4.4

2.5±4.4

3.5±4.3

7.0**

a<b, a<d

  1. Note. Numbers are Mean±SD or N (%). CES-D The Center for Epidemiologic Studies Depression Scale; IADLs Instrumental Activities of Daily Living; IL-6 Interleukin-6; hsCRP High sensitivity C-reactive protein. +total 9-item comorbidity score. #9-item CES-D score (excluding lonely). *p < 0.05; **p < 0.01; *** p < 0.001