Fig. 4

Forest plot of the multivariate analyses for the risk of metabolic adverse reactions. a Adjusted odds ratios and two-sided 95% confidence intervals of weight gain of more than 7% of initial weight after previous antipsychotic treatment compared to no previous antipsychotic treatment in different metabolic risk subgroups. b Adjusted odds ratios and two-sided 95% confidence intervals of HDL-C <1.04 mmol/L^–1 after previous antipsychotic treatment compared to no previous antipsychotic treatment in different metabolic risk subgroups. c Adjusted odds ratios and two-sided 95% confidence intervals of LDL-C ≥3.37 mmol/L^–1 after previous antipsychotic treatment compared to no previous antipsychotic treatment in different metabolic risk subgroups. APs, history of exposure to antipsychotics; high-metabolic-risk APs, history of exposure to high-metabolic-risk antipsychotics; low-metabolic-risk APs, history of exposure to low-metabolic-risk antipsychotics