Skip to main content

Table 3 Interaction effect of TPH2 methylation and ALFF ROI on HAMD 2-week reduction rate. mALFF mean Amplitude of low-frequency fluctuation, ROI Regions of interest, *p < 0.05, TPH2 Tryptophan hydroxylase2, SE standard error

From: Influence and interaction of resting state functional magnetic resonance and tryptophan hydroxylase-2 methylation on short-term antidepressant drug response

 

B value

Wald Chi-Square

SE

95% Wald Confidence Interval

p value

   

Lower Upper

 

TPH2-1–43

Low Level

-0.139

3.758

0.071

-0.280 -0.002

0.053

High Level

-

-

-

- -

-

mALFF ROI

Low Level

-0.186

8.103

0.653

- 0.314 -0.058

0 .004*

High Level

-

-

-

- -

-

TPH2-1–43 * mALFF ROI

Low Level * Low Level

0.190

4.168

0.931

0.008 0.373

0.041*

Low Level * High Level

-

-

-

- -

-

High Level * Low Level

-

-

-

- -

-

High Level * High Level

-

-

-

- -

-

Age

0.001

0.353

0.002

-0.163 0.055

0.552

Gender

-0.054

0.938

0.056

0.008 0.373

0.333