Table 1 Baseline characteristics of the sample as grouped by tHcy

Age (yrs)

69.5 ± 8.1

67.7 ± 7.7

70.5 ± 8.2

6.66

< 0.001*

Female,n (%)

806 (55.3)

374 (67.3)

432 (47.9)

52.22

< 0.001*

Education,n (%)

30.06

< 0.001*

 illiterate,n (%)

439 (30.1)

128 (23.0)

311 (34.5)

 primary school,n (%)

485 (33.3)

181 (32.6)

304 (33.7)

 High school,n (%)

534 (36.6)

247 (44.4)

287 (31.8)

BMI(kg/m²)

24.2 ± 4.1

24.3 ± 3.7

24.2 ± 4.3

0.88

0.378

Smoking,n (%)

458 (31.5)

124 (22.3)

334 (37.1)

34.55

< 0.001*

Drinking,n (%)

437 (30.0)

133 (23.9)

304 (33.8)

16.01

< 0.001*

SBP, mmHg

139.5 ± 20.4

137.2 ± 20.1

140.9 ± 20.5

3.30

< 0.001*

DBP, mmHg

76.7 ± 11.0

76.8 ± 11.3

76.7 ± 10.9

0.21

0.837

PP, mmHg

62.8 ± 17.4

60.4 ± 16.6

64.2 ± 17.8

4.01

< 0.001*

Fasting blood sugar, mmol/L

5.8 ± 1.7

5.9 ± 1.9

5.7 ± 1.7

2.95

0.081

UA, mmol/L

351.5 ± 96.8

331.1 ± 84.1

364.0 ± 101.9

6.38

< 0.001*

GDS score

5.7 ± 5.7

5.9 ± 5.0

5.6 ± 4.9

2.51

0.114

ADL score

6.2 ± 1.1

6.1 ± 0.6

6.2 ± 1.4

18.03

< 0.001*

IADL score

6.7 ± 2.2

6.4 ± 1.7

6.8 ± 2.3

48.42

< 0.001*

 ApoE, rs429358

0.42

0.520

  C/T, n (%)

184 (14.8)

74 (15.6)

110 (14.2)

  T/T, n (%)

1063 (85.2)

401 (84.4)

662 (85.8)

 ApoE, rs7412

0.24

0.624

  C/C, n (%)

1020 (82.7)

390 (83.3)

630 (82.2)

  C/T, n (%)

214 (17.3)

78 (16.7)

136 (17.8)