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Table 4 Subject serum parameters according to tHcy and ApoE rs429358 in Chinese adults

From: Combined homocysteine and apoE rs429358 and rs7412 polymorphism in association with serum lipid levels and cognition in Chinese community-dwelling older adults

 

HCY ≤ 15

HCY > 15

p value

ApoE rs429358(C/T)

ApoE rs429358(T/T)

ApoE rs429358(C/T)

ApoE rs429358(T/T)

N

74

401

110

662

 

TC, mmol/L

5.70(5.25,6.14)

5.83(5.65,6.01)

6.19(5.69,6.59)

5.81(5.68,5.95)

0.021*

TG, mmol/L

1.45(1.01,1.89)

1.63(1.46,1.81)

1.87(1.42,2.21)

1.55(1.42,1.68)

0.030*

LDL-C, mmol/L

3.01(2.71,3.30)

2.99(2.87,3.11)

3.02(1.15,1.33)

2.88(2.79,2.98)

0.407

HDL-C, mmol/L

1.20(1.10,1.31)

1.22(1.18,1.27)

1.24(1.12,1.25)

1.22(1.19,1.25)

0.482

HCY, mmol/L

12.47(5.61,19.32)

12.22(9.46,14.96)

24.40(18.25,30.55)

27.77(25.74,29.80`)

0.000*

  1. Data were expressed as mean (95% CI).The General Line Model (GLM) univariate analysis was used for data analysis. Factors including sex, age, BMI, smoking, alcohol drinking and physical activity wereadjusted. TC Total Cholesterol, TG Triglyceride, HDL-C High-density Lipoprotein Cholesterol, LDL-C Low-density Lipoprotein Cholesterol, HCY Homocysteine, ApoE Apolipoprotein E