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Table 4 Subject serum parameters according to tHcy and ApoE rs429358 in Chinese adults

From: Combined homocysteine and apoE rs429358 and rs7412 polymorphism in association with serum lipid levels and cognition in Chinese community-dwelling older adults

  HCY ≤ 15 HCY > 15 p value
ApoE rs429358(C/T) ApoE rs429358(T/T) ApoE rs429358(C/T) ApoE rs429358(T/T)
N 74 401 110 662  
TC, mmol/L 5.70(5.25,6.14) 5.83(5.65,6.01) 6.19(5.69,6.59) 5.81(5.68,5.95) 0.021*
TG, mmol/L 1.45(1.01,1.89) 1.63(1.46,1.81) 1.87(1.42,2.21) 1.55(1.42,1.68) 0.030*
LDL-C, mmol/L 3.01(2.71,3.30) 2.99(2.87,3.11) 3.02(1.15,1.33) 2.88(2.79,2.98) 0.407
HDL-C, mmol/L 1.20(1.10,1.31) 1.22(1.18,1.27) 1.24(1.12,1.25) 1.22(1.19,1.25) 0.482
HCY, mmol/L 12.47(5.61,19.32) 12.22(9.46,14.96) 24.40(18.25,30.55) 27.77(25.74,29.80`) 0.000*
  1. Data were expressed as mean (95% CI).The General Line Model (GLM) univariate analysis was used for data analysis. Factors including sex, age, BMI, smoking, alcohol drinking and physical activity wereadjusted. TC Total Cholesterol, TG Triglyceride, HDL-C High-density Lipoprotein Cholesterol, LDL-C Low-density Lipoprotein Cholesterol, HCY Homocysteine, ApoE Apolipoprotein E