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Table 5 Subject serum parameters according to tHcy and ApoE rs7412 in Chinese adults

From: Combined homocysteine and apoE rs429358 and rs7412 polymorphism in association with serum lipid levels and cognition in Chinese community-dwelling older adults

  HCY ≤ 15 HCY > 15 p value
ApoE rs7412(C/C) ApoE rs7412(C/T) ApoE rs7412(C/C) ApoE rs7412(C/T)
N 390 78 630 136  
TC, mmol/L 5.48(5.21,5.74) 5.67(5.53,5.97) 5.53(5.30,5.75) 5.85(5.75,5.96) 0.006*
TG, mmol/L 1.50(1.44,1.66) 1.57(1.39,1.69) 1.63(1.40,1.85) 1.89(1.63,2.16) 0.024*
LDL-C, mmol/L 3.04(2.96,3.12) 2.62(2.43, 2.80) 2.95(2.88,3.02) 2.33(2.06,2.61) < 0.001*
HDL-C, mmol/L 1.22(1.18,1.27) 1.21(1.18,1.25) 1.21(1.18,1.24) 1.28(1.19,1.34) 0.225
HCY, mmol/L 12.41(11.00,13.82) 12.46(9.36,15.55) 28.03(25.69,30.38) 26.47(22.26,30.68) <  0.001*
  1. Data were expressed as mean (95% CI). The General Line Model (GLM) univariate analysis was used for data analysis. Factors including sex, age, BMI, smoking, alcohol drinking and physical activity were adjusted. TC Total Cholesterol, TG Triglyceride, HDL-C High-density Lipoprotein Cholesterol, LDL-C Low-density Lipoprotein Cholesterol, HCY Homocysteine, ApoE Apolipoprotein E