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Table 7 Cognition according to tHcy and ApoE rs7412 in Chinese adults

From: Combined homocysteine and apoE rs429358 and rs7412 polymorphism in association with serum lipid levels and cognition in Chinese community-dwelling older adults

 

HCY ≤ 15

HCY > 15

p value

ApoE rs7412(C/C)

ApoE rs7412(C/T)

ApoE rs7412(C/C)

ApoE rs7412(C/T)

N

390

78

630

136

 

Orientation

8.92 (8.69,9.14)

9.14 (8.65, 9.62)

8.68 (8.48,8.88)

8.22 (7.80,8.65)

0.048*

Memory and delayed recall

5.40 (5.27,5.53)

5.38 (5.11,5.66)

5.23 (5.12,5.35)

5.50 (5.26,5.74)

0.170

Attention

4.16 (3.97,4.35)

4.37 (3.96,4.78)

3.90 (3.73,4.07)

3.62 (3.26,3.98)

0.014*

Language

6.60 (6.47,6.73)

6.77 (6.48,7.05)

6.44 (6.33,6.56)

6.55 (6.30,6.79)

0.153

Visual and executive

0.71 (0.66,0.75)

0.65 (0.54,0.75)

0.66 (0.62,0.70)

0.65 (0.56,0.75)

0.380

MMSE score

25.78 (25.24,26.32)

26.30 (25.13,27.47)

24.92 (24.43,25.40)

24.55 (23.52,25.57)

0.041*

  1. MMSE Mini-Mental State Examination, ApoE Apolipoprotein E. The General Line Model (GLM) univariate analysis was used for data analysis. Factors including age, sex, BMI, education, smoking, alcohol drinking and physical activity were adjusted. *p < 0.05 was considered as significance