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Table 1 Change in YMRS, HDRS, and CDRS scores over time (N = 26)

From: Findings from a pilot open-label trial of N-acetylcysteine for the treatment of pediatric mania and hypomania

 

Baseline

Endpoint†

Difference

Cohen’s d

(95% CI)

Test Statistic

P-Value

Mean ± SD

Mean ± SD

Mean ± SD

YMRS

23.8 ± 5.7

15.7 ± 10.1

-8.1 ± 8.5

0.99 (0.41, 1.56)

z = -7.19

 < .001

HDRS

15.3 ± 7.9

9.5 ± 8.5

-5.8 ± 7.2

0.70 (0.14, 1.26)

z = -3.95

 < .001

CDRS

37.1 ± 11.7

31.9 ± 14.7

-5.2 ± 10.7

0.39 (-0.16, 0.94)

z = -3.90

 < .001

  1. † Endpoint mean uses last observation carried forward for subjects who dropped prior to week 12
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BMC Psychiatry

ISSN: 1471-244X

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