Skip to main content

Table 3 Results of the Generalized Estimating Equation Model of HRV and Cohen’s d Effect Sizes

From: Effect of behavioral activation on time and frequency domain heart rate variability in older adults with subthreshold depression: a cluster randomized controlled trial in Thailand

 

Mean ± SD

Mean Difference (95% CI)

Cohen’s d Effect Size (95% CI)b

BA with usual care group

Usual care only group

Unadjusted

Adjusteda

SDNN (ms)

Baseline

23.10 ± 12.66

24.07 ± 11.28

-0.98 (-6.89, 4.94)

-0.48 (-6.69, 5.73)

 

3 months

29.85 ± 17.76

22.58 ± 9.27

7.26 (1.34, 13.18)*

7.75 (1.54, 13.96)*

-0.54 (-0.96, -0.09)

6 months

31.85 ± 18.89

22.09 ± 11.96

9.76 (3.84, 15.68)*

10.25 (4.04, 16.46)*

-0.62 (-1.06, -0.17)

9 months

31.83 ± 15.16

24.25 ± 12.16

7.59 (1.67, 13.50)*

8.08 (1.87, 14.29)*

-0.55 (-0.99, -0.11)

lnHF (ms2)

Baseline

4.81 ± 0.89

4.85 ± 0.96

-0.04 (-0.44, 0.37)

0.10 (-0.32, 0.52)

 

3 months

5.08 ± 1.06

5.02 ± 0.83

0.05 (-0.36, 0.45)

0.18 (-0.23, 0.60)

-0.05 (-0.48, 0.38)

6 months

5.26 ± 0.95

4.77 ± 0.92

0.49 (0.08, 0.90)*

0.63 (0.21, 1.05)*

-0.53 (-0.96, -0.08)

9 months

5.32 ± 1.08

4.88 ± 0.92

0.44 (0.04, 0.85)*

0.58 (0.16, 1.00)*

-0.44 (-0.88, -0.00)

LF (ms2)

Baseline

5.04 ± 1.09

5.06 ± 0.99

-0.01 (-0.46, 0.43)

0.13 (-0.33, 0.59)

 

3 months

5.19 ± 1.10

5.11 ± 0.89

0.08 (-0.37, 0.52)

0.22 (-0.24, 0.68)

-0.08 (-0.51, 0.36)

6 months

5.52 ± 1.12

4.86 ± 0.96

0.65 (0.20, 1.09)*

0.79 (0.33, 1.25)*

-0.62 (-1.06, -0.17)

9 months

5.67 ± 1.13

5.13 ± 1.04

0.53 (0.09, 0.98)*

0.67 (0.21, 1.13)*

-0.49 (-0.93, -0.05)

LF/HF (ms2)

Baseline

1.05 ± 0.18

1.06 ± 0.18

0.01c (-0.04, 0.06)

-0.00C (-0.04, 0.05)

 

3 months

1.03 ± 0.15

1.03 ± 0.17

0.01c (-0.04, 0.06)

-0.00C (-0.04, 0.05)

0.03 (-0.40, 0.46)

6 months

1.05 ± 0.16

1.03 ± 0.18

0.01c (-0.04, 0.06)

-0.00C (-0.04, 0.05)

-0.06 (-0.49, 0.38)

9 months

1.09 ± 0.14

1.06 ± 0.17

0.01c (-0.04, 0.06)

-0.00C (-0.04, 0.05)

-0.19 (-0.62, 0.25

  1. *p < 0.05
  2. a GEEs was used to analyze the mean difference adjusted for employment status and education level of each outcome
  3. b Cohen’s d effect size at 3, 6, and 9 months compared to baseline interpreted as follows: trivial (< .2), small (> .2), medium (> .5), large (> .8), and very large (> 1.3)
  4. c no interaction effect changes over time
  5. Abbreviations: BA behaviora l activation, lnHF high frequency, LF low frequency, LF/HF Low/high Frequency ratio, SDNN standard deviation of the NN interval, 95% CI 95% confidence interval