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Table 1 Demographic and biochemical parameters of MHD patients

From: High neutrophil-to-lymphocyte ratio is a significant predictor of depressive symptoms in maintenance hemodialysis patients: a cross-sectional study

Item

Total

No Depressive Symptoms (n = 122)

Mild Depressive Symptoms (n = 26)

Moderate/Moderately Severe Depressive Symptoms (n = 12)

F/χ2

P

Male, n (%)

90 (56.2%)

68 (55.7%)

14 (53.9%)

8 (66.7%)

0.603

0.740

Age (years)

55.5 ± 13.1

55.12 ± 12.3

56.62 ± 14.12

56.67 ± 19.27

0.189

0.828

Dialysis Duration (months)

73.5 (29.3, 150.8)

80 (30, 140)

58 (33, 168)

51 (19, 165)

1.349

0.510

SBP (mmHg)

144.8 ± 21.3

145.2 ± 20.9

144.2 ± 22.4

140.8 ± 25.0

0.241

0.786

DBP (mmHg)

81.3 ± 12.7

81.1 ± 12.6

82.6 ± 14.0

80.4 ± 11.3

0.176

0.839

Kt/V

1.32 ± 0.15

1.32 ± 0.14

1.29 ± 0.13

1.36 ± 0.19

1.17

0.313

Diabetic Mellitus (%)

23 (14.38%)

17 (13.93%)

4 (15.38%)

2 (16.5%)

0.148

0.105

Hypertension (%)

24 (15.0%)

18 (14.75%)

4 (15.38%)

2 (16.5%)

0.138

0.995

Transplantation, n (%)

  Yes

18 (11.3%)

18 (14.75%)

4 (15.38%)

2 (16.5%)

0.138

0.995

  No

142 (88.7%)

     

WBC (*109/L)

5.99 ± 1.73

5.90 ± 1.67

6.58 ± 2.12

5.72 ± 1.13

1.841

0.162

NEUT (*109/L)

4.04 ± 1.37

3.93 ± 1.26

4.50 ± 1.88

4.08 ± 0.98

1.876

0.157

LY (*109/L)

1.23 ± 0.48

1.23 ± 0.48

1.26 ± 0.39

1.11 ± 0.63

0.435

0.648

HGB (g/L)

114.96 ± 13.63

115.70 ± 12.84b

116.15 ± 16.29c

104.75 ± 12.02

3.778

0.025*

RDW (%)

14.14 ± 2.34

13.92 ± 1.77a

15.16 ± 4.15

14.20 ± 1.60

3.096

0.048*

PLT(*109/L)

184.32 ± 63.68

181.34 ± 59.70

201.04 ± 82.85

178.42 ± 54.89

1.083

0.341

NLR

3.74 ± 2.06

3.51 ± 1.42b

3.85 ± 1.78c

5.74 ± 5.17

6.947

0.001*

PLR

153.77 (120.05–199.50)

151.95 (122.64–191.21)

169.47 (125.45–207.48)

197.20 (103.64–232.38)

1.374

0.503

Alb(g/L)

42.02 ± 3.24

42.29 ± 2.89b

42.16 ± 3.03c

39.06 ± 5.31

5.793

0.004*

BUN (mmol/L)

22.8 ± 4.81

22.75 ± 4.48

23.07 ± 5.93

22.67 ± 5.76

0.051

0.951

Scr (umol/L)

859.91 ± 226.93

878.16 ± 213.29

834.16 ± 244.94

730.08 ± 289.72

2.576

0.079

BUA (umol/L)

431.19 ± 74.50

432.71 ± 71.68

444.88 ± 78.28

386.08 ± 84.12

2.722

0.069

CHO (mmol/L)

4.17 ± 1.04

4.22 ± 1.03

3.95 ± 1.16

4.10 ± 0.78

0.720

0.489

TG (mmol/L)

1.73 (1.15–2.65)

1.81 (1.20–2.65)

1.55 (1.15–2.82)

1.64 (0.95–2.88)

1.155

0.561

Ferritin (ng/ml)

160.5 (75.8–285.9)

156.5 (75.0–286.1)

189.9 (76.6–267.4)

160.8 (66.6–300.0)

0.205

0.903

hsCRP (mg/L)

3.67 (1.69–7.75)

3.45 (1.67–7.15)

3.67 (2.12–7.44)

8.21 (0.58–13.15)

0.947

0.623

Charlson Comorbidity Index Score

4.34 ± 1.75

4.28 ± 1.69

4.54 ± 1.68

4.58 ± 2.50

0.354

0.702

  1. ap: no depressive symptoms group vs mild depressive symptoms group
  2. b p: no depressive symptoms group vs moderate/moderately severe depressive symptoms group
  3. cp: mild depressive symptoms group vs moderate/moderately severe depressive symptoms group
  4. *Significant at p < 0.05
  5. Values are means ± standard deviations or medians (25th–75th percentiles), unless otherwise specified
  6. Abbreviations: SBP Systolic blood pressure, DBP Diastolic blood pressure, WBC White blood cell, NEUT Neutrophil, LY lymphocyte, HGB Hemoglobin, RDW Red cell distribution width, PLT Platelet, NLR Neutrophil-to-lymphocyte ratio, PLR Platelet-to-lymphocyte ratio, Alb Albumin, BUN Blood urea nitrogen, Scr Serum creatinine, UA Uric acid, CHO Total cholesterol, TG Triglyceride, hsCRP High-sensitivity C-reactive protein
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BMC Psychiatry

ISSN: 1471-244X

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