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Table 1 Demographic and biochemical parameters of MHD patients

From: High neutrophil-to-lymphocyte ratio is a significant predictor of depressive symptoms in maintenance hemodialysis patients: a cross-sectional study

Item Total No Depressive Symptoms (n = 122) Mild Depressive Symptoms (n = 26) Moderate/Moderately Severe Depressive Symptoms (n = 12) F/χ2 P
Male, n (%) 90 (56.2%) 68 (55.7%) 14 (53.9%) 8 (66.7%) 0.603 0.740
Age (years) 55.5 ± 13.1 55.12 ± 12.3 56.62 ± 14.12 56.67 ± 19.27 0.189 0.828
Dialysis Duration (months) 73.5 (29.3, 150.8) 80 (30, 140) 58 (33, 168) 51 (19, 165) 1.349 0.510
SBP (mmHg) 144.8 ± 21.3 145.2 ± 20.9 144.2 ± 22.4 140.8 ± 25.0 0.241 0.786
DBP (mmHg) 81.3 ± 12.7 81.1 ± 12.6 82.6 ± 14.0 80.4 ± 11.3 0.176 0.839
Kt/V 1.32 ± 0.15 1.32 ± 0.14 1.29 ± 0.13 1.36 ± 0.19 1.17 0.313
Diabetic Mellitus (%) 23 (14.38%) 17 (13.93%) 4 (15.38%) 2 (16.5%) 0.148 0.105
Hypertension (%) 24 (15.0%) 18 (14.75%) 4 (15.38%) 2 (16.5%) 0.138 0.995
Transplantation, n (%)
  Yes 18 (11.3%) 18 (14.75%) 4 (15.38%) 2 (16.5%) 0.138 0.995
  No 142 (88.7%)      
WBC (*109/L) 5.99 ± 1.73 5.90 ± 1.67 6.58 ± 2.12 5.72 ± 1.13 1.841 0.162
NEUT (*109/L) 4.04 ± 1.37 3.93 ± 1.26 4.50 ± 1.88 4.08 ± 0.98 1.876 0.157
LY (*109/L) 1.23 ± 0.48 1.23 ± 0.48 1.26 ± 0.39 1.11 ± 0.63 0.435 0.648
HGB (g/L) 114.96 ± 13.63 115.70 ± 12.84b 116.15 ± 16.29c 104.75 ± 12.02 3.778 0.025*
RDW (%) 14.14 ± 2.34 13.92 ± 1.77a 15.16 ± 4.15 14.20 ± 1.60 3.096 0.048*
PLT(*109/L) 184.32 ± 63.68 181.34 ± 59.70 201.04 ± 82.85 178.42 ± 54.89 1.083 0.341
NLR 3.74 ± 2.06 3.51 ± 1.42b 3.85 ± 1.78c 5.74 ± 5.17 6.947 0.001*
PLR 153.77 (120.05–199.50) 151.95 (122.64–191.21) 169.47 (125.45–207.48) 197.20 (103.64–232.38) 1.374 0.503
Alb(g/L) 42.02 ± 3.24 42.29 ± 2.89b 42.16 ± 3.03c 39.06 ± 5.31 5.793 0.004*
BUN (mmol/L) 22.8 ± 4.81 22.75 ± 4.48 23.07 ± 5.93 22.67 ± 5.76 0.051 0.951
Scr (umol/L) 859.91 ± 226.93 878.16 ± 213.29 834.16 ± 244.94 730.08 ± 289.72 2.576 0.079
BUA (umol/L) 431.19 ± 74.50 432.71 ± 71.68 444.88 ± 78.28 386.08 ± 84.12 2.722 0.069
CHO (mmol/L) 4.17 ± 1.04 4.22 ± 1.03 3.95 ± 1.16 4.10 ± 0.78 0.720 0.489
TG (mmol/L) 1.73 (1.15–2.65) 1.81 (1.20–2.65) 1.55 (1.15–2.82) 1.64 (0.95–2.88) 1.155 0.561
Ferritin (ng/ml) 160.5 (75.8–285.9) 156.5 (75.0–286.1) 189.9 (76.6–267.4) 160.8 (66.6–300.0) 0.205 0.903
hsCRP (mg/L) 3.67 (1.69–7.75) 3.45 (1.67–7.15) 3.67 (2.12–7.44) 8.21 (0.58–13.15) 0.947 0.623
Charlson Comorbidity Index Score 4.34 ± 1.75 4.28 ± 1.69 4.54 ± 1.68 4.58 ± 2.50 0.354 0.702
  1. ap: no depressive symptoms group vs mild depressive symptoms group
  2. b p: no depressive symptoms group vs moderate/moderately severe depressive symptoms group
  3. cp: mild depressive symptoms group vs moderate/moderately severe depressive symptoms group
  4. *Significant at p < 0.05
  5. Values are means ± standard deviations or medians (25th–75th percentiles), unless otherwise specified
  6. Abbreviations: SBP Systolic blood pressure, DBP Diastolic blood pressure, WBC White blood cell, NEUT Neutrophil, LY lymphocyte, HGB Hemoglobin, RDW Red cell distribution width, PLT Platelet, NLR Neutrophil-to-lymphocyte ratio, PLR Platelet-to-lymphocyte ratio, Alb Albumin, BUN Blood urea nitrogen, Scr Serum creatinine, UA Uric acid, CHO Total cholesterol, TG Triglyceride, hsCRP High-sensitivity C-reactive protein