Fig. 1

Most common reasons for changes in treatment pattern. a Treatment discontinuation. b Treatment interruption/drug holiday. c Dosage increase. d Dosage decrease. Notes: [1] Other reasons for treatment discontinuation included cost considerations, social stigma associated with ADHD medication, treatment monitoring becoming burdensome, treatment no longer being appropriate, member of patient’s household misuse of medication or addiction, and other patient-driven and physician-driven reasons. [2] Other reasons for treatment interruption/drug holiday included social stigma associated with ADHD medication, testing treatment efficacy or if treatment was still needed, and other patient-driven reason. [3] Other reasons for dosage increase included change in insurance coverage, leveraging the treatment’s side effects (e.g., weight loss in obese patient), weight gain (e.g., for dose dependent treatment), and other patient-driven and physician-driven reasons. [4] Other reasons for dosage decrease included change in insurance coverage and other patient-driven and physician-driven reasons