Table 2 Comparison of the clinical characteristics of participants with SUD (with and without active consumption) and without SUD

Age at first consumption (years)

–

15 (12, 17)

10 (9, 16)

0.093

BIS-11 Total

53.0 (43.0, 70.0)

58.0 (46.0, 64.0)

65.0 (56.5, 70.5)

0.082

Attentional

9.0 (5.0, 11.0)

9.0 (6.0, 11.0)

9.0 (8.0, 10.5)

0.370

Cognitive instability

5.0 (3.0, 7.0)

6.0 (4.0, 8.0)

7.0 (5.0, 8.0)

0.090

Motor

10.0 (7.0, 14.0)

12.0 (7.0, 15.0)

130 (11.0, 15.5)

0.166

Perseverence

6.0 (4.0, 8.0)

7.0 (5.0, 8.0)

7.0 (6.5, 8.5)

0.136

Self-control

8.0 (6.0, 13.0)

9.0 (6.0, 15.0)

13.0 (11.0, 17.0)

0.034

Cognitive complexity

11.0 (8.0, 14.0)

11.0 (7.0, 13.0)

11.0 (8.5, 12.0)

0.503

Attentional

15.0 (9.0, 17.0)

15.0 (11.0, 19.0)

15.5 (13.0, 18.5)

0.146

Motor

16.0 (13.0, 21.0)

20.0 (14.0, 24.0)

20.5 (17.5, 23.5)

0.910

Non-planning

20.0 (14.0, 26.0)

22.0 (13.0, 29.0)

23.5 (21.0, 28.5)

0.144

 Medical

–

0.0 (0.0, 0.7)

0.0 (0.0, 0.7)

0.755

 Job satisfaction

–

0.5 (0.0, 0.8)

0.5 (0.2, 1.0)

0.480

 Alcohol use

–

0.0 (0.0, 0.0)

0.0 (0.0, 0.0)

0.710

 Drug use

–

0.0 (0.0, 0.1)

0.3 (0.1, 0.4)

0.001

 Legal status

–

0.2 (0.0, 0.4)

0.4 (0.3, 0.6)

0.041

 Family

–

0.0 (0.0, 0.4)

0.0 (0.0, 0.2)

0.940

 Social relations

–

0.0 (0.0, 0.4)

0.0 (0.0, 0.4)

1.000

 Psychiatric status

–

0.0 (0.0, 0.4)

0.4 (0.1, 0.5)

0.093

Heroin use (days of the previous month)

–

–

27 (0, 30)

–

Cannabis use (days of the previous month)

–

–

20 (1, 30)

–

Methadone dosage (mg)

–

25.0 (18.0, 32.0)

28.0 (25.0, 33.0)

0.290

s-COMT activity (pmol/mg prot/h)

19.14 ± 4.12

17.98 ± 3.87

18.42 ± 4.19

0.707