Anatomical distance affects functional connectivity at rest in medicine-free obsessive–compulsive disorder

BMC Psychiatry

Table 1 Demographic and clinical characteristics of participants

	OCD patients (n = 40)	HCs (n = 38)	X²/t	p
Age (years)	27.28 ± 8.16	27.18 ± 8.33	0.05	0.71
Sex (male/female)	27/13	25/13	0.03	0.87
Education (years)	13.40 ± 2.87	13.74 ± 3.03	-0.50	0.83
Illness duration (months)	66.68 ± 75.54	–	–	–
Y-BOCS total score	24.90 ± 5.73	1.13 ± 0.88	25.27	p < 0.01
Y-BOCS obsessive thinking	12.85 ± 4.25	0.37 ± 0.49	17.98	p < 0.01
Y-BOCS compulsive behavior	12.05 ± 4.62	0.74 ± 0.72	14.92	p < 0.01
17-HAMD	8.05 ± 4.40	1.45 ± 0.95	9.04	p < 0.01
HAMA	10.83 ± 6.55	1.16 ± 1.00	9.00	p < 0.01
FD	0.04 ± 0.02	0.03 ± 0.01	1.25	0.13

There was no significant difference between OCD patients and HCs in age, sex, education level, and FD values (all p values > 0.05)
Abbreviations: OCD obsessive–compulsive disorder, HCs healthy controls, Y-BOCS Yale-Brown Obsessive–Compulsive Scale, 17-HAMD 17-item Hamilton Depression Rating Scale, HAMA Hamilton Anxiety Rating Scale, FD framewise displacement

ISSN: 1471-244X