Anatomical distance affects functional connectivity at rest in medicine-free obsessive–compulsive disorder

BMC Psychiatry

Table 2 Brain regions with altered short- and long-range functional connectivity in patients with OCD

Cluster location	Peak (MNI)			Number of voxels	T value
Cluster location	x	y	z	Number of voxels	T value
spFC
Left Precentral Gyrus/Postcentral Gyrus	-45	-9	30	100	-5.5672
lpFC
Left Precentral Gyrus/Postcentral Gyrus	-45	-9	30	104	-5.4304
Right Thalamus/Caudate	18	-9	21	52	4.5918
Left Thalamus	-15	-15	9	66	4.6094
Left Inferior Parietal Lobule	-45	-45	39	50	4.4068
Left Cerebellum VI/Crus I	-30	-72	-27	86	5.9268

The significance level was set at p < 0.05 for multiple comparisons corrected by Gaussian Random Field (GRF) theory (voxel significance: p < 0.001, cluster significance: p < 0.05). Age, sex, education level, mean FD values, 17-HAMD and HAMA scores were used as covariates to minimize the potential effects of these variables
MNI Montreal Neurological Institute, spFC short-range positive functional connectivity, lpFC long-range positive functional connectivity, FD framewise displacement, 17-HAMD 17-item Hamilton Depression Rating Scale, HAMA Hamilton Anxiety Rating Scale

ISSN: 1471-244X