Table 1 Participant timeline and outcome assessments
Timepoint | Study Period | |||||
|---|---|---|---|---|---|---|
Enrolment | Allocation | Post-allocation | ||||
-t1 | 0 | t1: Pretest | t2: Posttest | t3: Follow-up 1 (3 months) | t4: Follow-up 2 (6 months) | |
Enrolment | ||||||
 Eligibility screen | ✓ | |||||
 Informed consent | ✓ | |||||
 Allocation | ✓ | |||||
Interventions | ||||||
 Transdiagnostic guided internet-delivered intervention with synchronous assistance (UP- guided) | ||||||
 Transdiagnostic self-guided internet-delivered intervention (UP-unguided) | ||||||
 Wait list control (WL) | ||||||
Assessments | ||||||
Primary outcome measure | ||||||
 Mini International Neuropsychiatric Interview | ✓ | |||||
 Symptom checklist (SCL-90) | ✓ | ✓ | ||||
 Beck's Anxiety Inventory (BAI) | ✓ | ✓ | ✓ | ✓ | ||
 Beck's Depression Inventory (BDI-II) | ✓ | ✓ | ✓ | ✓ | ||
 Posttraumatic Stress Disorder Checklist for DSM-5 (PCL-5) | ✓ | ✓ | ✓ | ✓ | ||
 Scale of Difficulties in Emotional Regulation (DERS) | ✓ | ✓ | ✓ | ✓ | ||
Secondary outcome measures (during intervention) | ||||||
 General Anxiety and the Impairment Severity Scale (OASIS) | ||||||
 General Depression and the Impairment Gravity Scale (ODSIS) | ||||||
Secondary outcome measures | ||||||
 Acceptance/Satisfaction/Usability Measures | ✓ | |||||