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Table 1 Demographics, health characteristics of respondents with depression versus without depression diagnosis and across severity groups

From: Humanistic and economic burden associated with depression in the United States: a cross-sectional survey analysis

Variable

Respondents without depression diagnosisb*

n = 30,478

Respondents with depression diagnosisa

Total (all symptom levels)*

n = 8853

No/minimal symptoms#

n = 1876

Mild symptoms#

n = 2801

Moderate symptoms#

n = 1938

Moderately severe symptoms#

n = 1376

Severe symptoms#

n = 862

Demographic characteristics

Age (years), mean ± SD

43.9 ± 13.6

39.9 ± 14.1

42.1 ± 13.8

41.0 ± 14.0

39.0 ± 14.2

37.8 ± 13.8

37.1 ± 14.1

Female, n (%)

15600 (51.2)

6282 (71.0)

1265 (67.4)

1968 (70.3)

1416 (73.1)

993 (72.2)

640 (74.2)

Race/ethnicity, n (%)

  Non-Hispanic white

17860 (58.6)

5817 (65.7)

1244 (66.3)

1918 (68.5)

1259 (65.0)

865 (62.9)

531 (61.6)

  Non-Hispanic black

3866 (12.7)

818 (9.2)

197 (10.5)

241 (8.6)

169 (8.7)

134 (9.7)

77 (8.9)

  Hispanic

3373 (11.1)

1184 (13.4)

228 (12.2)

348 (12.4)

273 (14.1)

186 (13.5)

149 (17.3)

  Other ethnicity

5379 (17.6)

1034 (11.7)

207 (11.0)

294 (10.5)

237 (12.2)

191 (13.9)

105 (12.2)

Marital status, n (%)

  Single

12301 (40.4)

4825 (54.5)

936 (49.9)

1501 (53.6)

1066 (55.0)

789 (57.3)

533 (61.8)

  Married/living with partner

18096 (59.4)

4015 (45.4)

937 (49.9)

1299 (46.4)

867 (44.7)

587 (42.7)

325 (37.7)

  Decline to answer

81 (0.3)

13 (0.1)

3 (0.2)

1 (0.0)

5 (0.3)

0 (0.0)

4 (0.5)

Education level, n (%)

  Less than college educated

13140 (43.1)

5437 (61.4)

1003 (53.5)

1649 (58.9)

1240 (64.0)

930 (67.6)

615 (71.3)

  College educated

17289 (56.7)

3401 (38.4)

866 (46.2)

1149 (41.0)

694 (35.8)

446 (32.4)

246 (28.5)

  Decline to answer

49 (0.2)

15 (0.2)

7 (0.4)

3 (0.1)

4 (0.2)

0 (0.0)

1 (0.1)

Annual household income, n (%)

  < $25 K

3420 (11.2)

2185 (24.7)

349 (18.6)

645 (23.0)

491 (25.3)

427 (31.0)

273 (31.7)

  $25 K to < $50 K

5835 (19.1)

2499 (28.2)

464 (24.7)

798 (28.5)

563 (29.1)

418 (30.4)

256 (29.7)

  $50 K to < $75 K

5775 (18.9)

1637 (18.5)

383 (20.4)

560 (20.0)

355 (18.3)

207 (15.0)

132 (15.3)

  $75 K or more

13567 (44.5)

2120 (23.9)

598 (31.9)

691 (24.7)

419 (21.6)

264 (19.2)

148 (17.2)

  Decline to answer

1881 (6.2)

412 (4.7)

82 (4.4)

107 (3.8)

110 (5.7)

60 (4.4)

53 (6.1)

Employed, n (%)

22073 (72.4)

5014 (56.6)

1208 (64.4)

1638 (58.5)

1058 (54.6)

706 (51.3)

404 (46.9)

Has health insurance, n (%)

27719 (90.9)

8030 (90.7)

1764 (94.0)

2557 (91.3)

1747 (90.1)

1219 (88.6)

743 (86.2)

Body mass index, n (%)

  Underweight (< 18.5)

732 (2.4)

256 (2.9)

48 (2.6)

68 (2.4)

59 (3.0)

48 (3.5)

33 (3.8)

  Normal weight (18.5–24.9)

11476 (37.7)

2540 (28.7)

580 (30.9)

808 (28.8)

543 (28.0)

391 (28.4)

218 (25.3)

  Overweight (25.0–29.9)

9716 (31.9)

2258 (25.5)

550 (29.3)

745 (26.6)

449 (23.2)

328 (23.8)

186 (21.6)

  Obese (30.0–39.9)

6308 (20.7)

2542 (28.7)

494 (26.3)

811 (29.0)

586 (30.2)

381 (27.7)

270 (31.3)

  Morbidly obese (≥ 40)

1187 (3.9)

973 (11.0)

147 (7.8)

276 (9.9)

232 (12.0)

196 (14.2)

122 (14.2)

  Decline to answer

1059 (3.5)

284 (3.2)

57 (3.0)

93 (3.3)

69 (3.6)

32 (2.3)

33 (3.8)

Smoking behavior, n (%)

  Never smoked

21814 (71.6)

4844 (54.7)

1095 (58.4)

1518 (54.2)

1072 (55.3)

682 (49.6)

477 (55.3)

  Former smoker

5546 (18.2)

2275 (25.7)

466 (24.8)

744 (26.6)

495 (25.5)

365 (26.5)

205 (23.8)

  Current smoker

3118 (10.2)

1734 (19.6)

315 (16.8)

539 (19.2)

371 (19.1)

329 (23.9)

180 (20.9)

Alcohol use, n (%)

20441 (67.1)

5839 (66.0)

1268 (67.6)

1918 (68.5)

1258 (64.9)

879 (63.9)

516 (59.9)

Regularly exercised

22372 (73.4)

5192 (58.6)

1215 (64.8)

1707 (60.9)

1091 (56.3)

748 (54.4)

431 (50.0)

CCI, mean ± SD

0.14 ± 0.61

0.44 ± 1.08

0.36 ± 0.98

0.42 ± 1.08

0.48 ± 1.11

0.49 ± 1.16

0.51 ± 1.08

Depression symptoms at the time of diagnosis

  Depressed mood and other emotional problems, n (%)

-

7791 (88.0)

1593 (84.9)

2478 (88.5)

1718 (88.6)

1216 (88.4)

786 (91.2)

  Eating pattern changes, n (%)

-

1859 (21.0)

319 (17.0)

570 (20.3)

462 (23.8)

318 (23.1)

190 (22.0)

  Sleep pattern changes, n (%)

-

3876 (43.8)

730 (38.9)

1231 (43.9)

906 (46.7)

642 (46.7)

367 (42.6)

  Mental changes, n (%)

-

4340 (49.0)

748 (39.9)

1362 (48.6)

992 (51.2)

723 (52.5)

515 (59.7)

  Social problems, n (%)

-

2810 (31.7)

481 (25.6)

854 (30.5)

628 (32.4)

503 (36.6)

344 (39.9)

  Physical problems, n (%)

-

1342 (15.2)

251 (13.4)

433 (15.5)

293 (15.1)

230 (16.7)

135 (15.7)

Anxiety and sleep problems

  Diagnosed with anxiety totalc n (%)

1668 (5.5)

6481 (73.2)

1157 (61.7)

2007 (71.7)

1468 (75.7)

1114 (81.0)

735 (85.3)

  Diagnosed with any sleep problem, n (%)

1995 (6.5)

3531 (39.9)

471 (25.1)

1073 (38.3)

866 (44.7)

646 (46.9)

475 (55.1)

Prescription use

  For anxiety totalc, n (%)

815 (2.7)

3892 (44.0)

708 (37.7)

1183 (42.2)

897 (46.3)

661 (48.0)

443 (51.4)

  For sleep totald, n (%)

715 (2.3)

1536 (17.4)

200 (10.7)

488 (17.4)

363 (18.7)

276 (20.1)

209 (24.2)

GAD-7 scores

  GAD-7 score, mean ± SD

1.16 ± 2.10

8.00 ± 5.57

3.10 ± 3.26

6.33 ± 3.99

9.01 ± 4.41

12.16 ± 4.59

15.15 ± 4.84

  1. aRespondents with depression diagnosis: those who self-reported physician diagnosis of depression and reported experiencing depression in the past 12 months
  2. bRespondents without depression diagnosis: those who had no self-reported physician diagnosis of depression, reported not experiencing depression in the past 12 months, and had PHQ-9 scores ≤ 4
  3. cAnxiety total: Anxiety, generalized anxiety, social anxiety, PTSD, OCD, panic disorder, phobias
  4. dSleep total: Sleep difficulties, insomnia, sleep apnea
  5. *P < 0.001 for all variables compared between ‘with depression diagnosis (total)’ vs. ‘without depression diagnosis’ groups
  6. #P < 0.001 for all variables across all severity groups using an overall omnibus test, except “physical problems” for which P = 0.176
  7. CCI Charlson comorbidity index, GAD-7 Generalized anxiety disorder-7 scale, OCD Obsessive–compulsive disorder, PHQ-9 The Patient Health Questionnaire 9, PTSD Post-traumatic stress disorder, SD Standard deviation