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Table 3 Primary outcomes: PANS scale and CGI scores at Baseline, Visit 1 and Visit 3 (mean, SD). Secondary outcomes: CY-BOCS scores and school attendance at Baseline and Visit 3

From: Paediatric Acute-onset Neuropsychiatric Syndrome (PANS) and intravenous immunoglobulin (IVIG): comprehensive open-label trial in ten children

PANS Scale (Total)

Mean

SD

ES

P-value

Baseline

81.2

7.82

  

Visit 1

54.0

16.80

  

Visit 3

47.4

14.64

2.64

 = .005

(n = 10)

PANS Scale (Symptom)

Baseline

41.3

5.29

  

Visit 1

27.0

9.55

  

Visit 3

24.9

7.00

3.15

 = .005

(n = 10)

PANS Scale (Impairment)

Baseline

39.8

3.39

  

Visit 1

27.0

7.53

  

Visit 3

22.5

7.91

2.07

 = .005

(n = 10)

CGI-S

Baseline

5.8

0.42

  

Visit 1

3.9

0.74

  

Visit 3

3.0

1.05

2.79

 = .004

(n = 10)

CGI-I

Visit 1

2.1

0.57

  

Visit 3

1.8

0.79

  

(n = 10)

CY-BOCS (Total)

Baseline

24

7.80

  

Visit 3

17.8

7.67

1.48

 = .005

(n = 10)

Days absent from school

Baseline

9.5

6.70

 

 = .005

Visit 1

6.2

6.53

  

Visit 3

2.7

3.53

1.06

 

  (n = 10)

  1. Means, SDs, Effect Size (ES, Cohen’s D with Hedges’ correction), p-values from non-parametric Wilcoxon signed ranks test