Characteristic | Control | A) | B) | ||||||
---|---|---|---|---|---|---|---|---|---|
(appendicitis) N = 664b | All PDc N = 39,177 | P-value | Depression N = 15,421 | Schizophrenia N = 840 | Bipolar N = 186 | Anxiety N = 7522 | Multiple PD N = 15,208 | P-value | |
Median age at diagnosis in years (range) | 67 (15–85) | 69 (14–85) | 0.02 | 69 (17–85) | 74 (17–85) | 69 (29–85) | 70 (19–85) | 67 (14–85) | < 0.001 |
Male, n (%) | 437 (66%) | 17,336 (44%) | < 0.001 | 7050 (46%) | 493 (59%) | 87 (47%) | 3747 (50%) | 5959 (39%) | < 0.001 |
Cancer type, n (%) | |||||||||
Lung | 125 (19%) | 13,786 (35%) | < 0.001 | 5599 (36%) | 337 (40%) | 79 (43%) | 2680 (36%) | 5091 (34%) | < 0.001 |
Colorectal | 365 (55%) | 10,988 (28%) | 4138 (27%) | 208 (25%) | 45 (24%) | 2060 (27%) | 4537 (30%) | ||
Esophagus | 14 (2%) | 869 (2%) | 354 (2%) | 26 (3%) | a | 182 (2%) | 304 (2%) | ||
Stomach | 23 (4%) | 1677 (4%) | 679 (4%) | 60 (7%) | 7 (4%) | 348 (5%) | 583 (4%) | ||
Lip, oral cavity, pharynx | 18 (3%) | 1968 (5%) | 715 (5%) | 25 (3%) | 9 (5%) | 353 (5%) | 866 (6%) | ||
Liver | 19 (3%) | 952 (2%) | 404 (3%) | 31 (4%) | a | 174 (2%) | 340 (2%) | ||
Pancreas | 29 (4%) | 2520 (6%) | 1087 (7%) | 47 (6%) | 12 (7%) | 523 (7%) | 851 (6%) | ||
Larynx | 7 (1%) | 448 (1%) | 196 (1%) | 7 (1%) | a | 79 (1%) | 164 (1%) | ||
Cervix | 11 (2%) | 1006 (3%) | 321 (2%) | 10 (1%) | a | 141 (2%) | 531 (4%) | ||
Kidney | 27 (4%) | 2308 (6%) | 846 (6%) | 28 (3%) | 9 (5%) | 437 (6%) | 988 (7%) | ||
Bladder | 26 (4%) | 2101 (5%) | 859 (6%) | 53 (6%) | 14 (8%) | 425 (6%) | 750 (5%) | ||
AML | a | 554 (1%) | 223 (1%) | 8 (1%) | a | 120 (2%) | 203 (1%) | ||
Mean years of follow-up (to death) | 6.7 | 8.8 | < 0.001 | 8.9 | 9.1 | 9.5 | 8.8 | 8.6 | < 0.001 |
Died during study period, n (%) | 359 (54%) | 25,230 (64%) | < 0.001 | 10,425 (68%) | 710 (85%) | 148 (80%) | 5045 (67%) | 8902 (59%) | < 0.001 |
Tobacco-related deaths, n (%)d | |||||||||
Total person-years of follow-up | 2601 | 123,308 | – | 42,406 | 1440 | 579 | 22,105 | 56,779 | – |