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Table 1 Cohort demographic and follow-up information, comparing A) all psychiatric disorders and B) psychiatric disorder sub-cohorts to the appendicitis control group

From: Population-based comparison of cancer survival outcomes in patients with and without psychiatric disorders

Characteristic

Control

A)

B)

(appendicitis) N = 664b

All PDc

N = 39,177

P-value

Depression

N = 15,421

Schizophrenia

N = 840

Bipolar

N = 186

Anxiety

N = 7522

Multiple PD

N = 15,208

P-value

Median age at diagnosis in years (range)

67 (15–85)

69 (14–85)

0.02

69 (17–85)

74 (17–85)

69 (29–85)

70 (19–85)

67 (14–85)

< 0.001

Male, n (%)

437 (66%)

17,336 (44%)

< 0.001

7050 (46%)

493 (59%)

87 (47%)

3747 (50%)

5959 (39%)

< 0.001

Cancer type, n (%)

 Lung

125 (19%)

13,786 (35%)

< 0.001

5599 (36%)

337 (40%)

79 (43%)

2680 (36%)

5091 (34%)

< 0.001

 Colorectal

365 (55%)

10,988 (28%)

4138 (27%)

208 (25%)

45 (24%)

2060 (27%)

4537 (30%)

 Esophagus

14 (2%)

869 (2%)

354 (2%)

26 (3%)

a

182 (2%)

304 (2%)

 Stomach

23 (4%)

1677 (4%)

679 (4%)

60 (7%)

7 (4%)

348 (5%)

583 (4%)

 Lip, oral cavity, pharynx

18 (3%)

1968 (5%)

715 (5%)

25 (3%)

9 (5%)

353 (5%)

866 (6%)

 Liver

19 (3%)

952 (2%)

404 (3%)

31 (4%)

a

174 (2%)

340 (2%)

 Pancreas

29 (4%)

2520 (6%)

1087 (7%)

47 (6%)

12 (7%)

523 (7%)

851 (6%)

 Larynx

7 (1%)

448 (1%)

196 (1%)

7 (1%)

a

79 (1%)

164 (1%)

 Cervix

11 (2%)

1006 (3%)

321 (2%)

10 (1%)

a

141 (2%)

531 (4%)

 Kidney

27 (4%)

2308 (6%)

846 (6%)

28 (3%)

9 (5%)

437 (6%)

988 (7%)

 Bladder

26 (4%)

2101 (5%)

859 (6%)

53 (6%)

14 (8%)

425 (6%)

750 (5%)

 AML

a

554 (1%)

223 (1%)

8 (1%)

a

120 (2%)

203 (1%)

Mean years of follow-up (to death)

6.7

8.8

< 0.001

8.9

9.1

9.5

8.8

8.6

< 0.001

Died during study period, n (%)

359 (54%)

25,230 (64%)

< 0.001

10,425 (68%)

710 (85%)

148 (80%)

5045 (67%)

8902 (59%)

< 0.001

Tobacco-related deaths, n (%)d

         

Total person-years of follow-up

2601

123,308

42,406

1440

579

22,105

56,779

  1. All PD = any psychiatric disorder diagnosis; Schizophrenia = schizophrenia and related diseases; Bipolar = bipolar disorder; Anxiety = anxiety disorders; Multiple PD = diagnosis with 2 or more PD on same day
  2. acell sizes less than 5 are suppressed as per Population Data BC guidelines
  3. bAppendicitis cases were identified using ICD-9 codes: 540–542 and ICD-10 codes: K35-K37
  4. cPD cases were identified using ICD-9 codes: Psychotic Conditions: (293.84295296.0–296.8297298), Neurotic Disorders (300.0–300.5300.89300.9), Dependence Syndromes (303,304.0, 304.2, 304.3, 304.4), Non-dependent Substance Abuse (305.0, 305.2, 305.5, 305.6, 305.7), Acute Reactions to Stress and Adjustment Reaction (308.0–308.9309.8), Depressive Disorder (311), Disturbance of Emotions Related to Childhood and Adolescence (313.0–313.83), Poisoning by Substances (965.0968.5969.7980.0), Other (E850.0, E850.1, E850.2 E854.2 E855.2) and ICD-10 codes: Organic Mental Disorders (F06.4), Mental and Behavioural Disorders due to Psychoactive Substance Use (F10 F11.1, F11.2 F12.1, F12.2 F14.1, F14.2 F15.1, F15.2), Schizophrenia, Schizotypal, and Delusional Disorders (F20 F21 F22 F24 F28 F29), Mood Disorders (F30 F31.0, F31.1, F31.2, F31.3, F31.4, F31.5, F31.6, F31.8, F31.9 F32.2, F32.3, F32.8 F33.2, F33.3, F33.4, F33.8, F33.9 F34.1 F38.1), Neurotic, Stress-Related and Somatoform Disoders (F40 F41 F42 F43.0, F43.1, F43.9 F44 F48.0, F48.8, F48.9), Postnatal and Postpartum Depression (F53.0), Disturbance of Emotions and Behaviour Related to Childhood and Adolescence (F93, F94), Poisoning (T40.0, T40.1, T40.3, T40.4, T40.5 T43.6 T51.0 X41 X42)
  5. dTobacco-related deaths were identified using the ICD 9 codes: Malignant Neoplasms of Lip, Oral Cavity and Pharynx (140–149), Malignant Neoplasm of Digestive Organs and Peritoneum (150, 151, 157), Malignant Neoplasm of Respiratory and Intrathoracic Organs (161, 162), Malignant Neoplasm of Genitourinary Organs (180, 188, 189), Malignant Neoplasm of Lymphatic and Haematopoietic Tissue (205.0), Ischemic Heart Disease (410–414), Cardiovascular Disease (unspecified; 429.2), Acute Rheumatic Fever and Chronic Rheumatic Heart Disease (390–398), Disease of Pulmonary Circulation (415–417), Other Forms of Heart Disease (420–429.1, 429.3–429.9), Cerebrovascular Disease (430–438), Disease of Arteries, Arterioles, and Capillaries (440, 441, 442–448), Pneumonia and Influenza (480–487), Chronic Obstructive Pulmonary Disease and Allied Conditions (490–492, 496) and ICD-10 codes: Malignant Neoplasm of Lip, Oral Cavity, and Pharynx (C00-C14), Malignant Neoplasm of Digestive Organs (C15, C16, C25), Malignant Neoplasm of Respiratory and Intrathoracic Organs (C32-C34), Malignant Neoplasm of Female Genital Organs (C53), Malignant Neoplasm of Urinary Tract (C64, C65, C67), Malignant Neoplasm of Lymphoid, Haematopoietic, and Related Tissue (C92.0), Influenza and Pneumonia (J10-J18), Chronic Lower Respiratory Diseases (J40-J44), Other (120–125, 100–109, 126–151, 160–169, 170–178)