Table 2 Multivariable analysis to assess the effect of PD diagnosis on overall and TR cancer-specific survival, controlling for age, gender, cancer type and diagnosis year

Psychiatric disorder

Appendicitis (control)

1

reference

–

1

reference

–

Depression

1.13

0.99–1.29

0.07

1.16

1.04–1.29

< 0.01

Schizophrenia

1.56

1.33–1.83

< 0.01

1.62

1.43–1.84

< 0.01

Bipolar disorder

1.20

0.92–1.57

0.19

1.35

1.12–1.64

< 0.01

Anxiety

1.07

0.94–1.23

0.29

1.07

0.96–1.19

0.24

Age (continuous yearly)

1.02

(1.02–1.02)

< 0.01

1.03

1.03–1.03

< 0.01

Gender

Male

1

reference

–

1

reference

–

Female

0.93

(0.90–0.97)

< 0.01

0.90

0.88–0.93

< 0.01

Diagnosis year

1.06

1.05–1.06

< 0.01

0.98

0.98–0.98

< 0.01

Cancer type

Lung

1

reference

–

1

reference

–

Lip, oral cavity, pharynx

0.26

0.23–0.29

< 0.01

0.32

0.29–0.35

< 0.01

Esophagus

0.92

0.82–1.02

0.11

0.92

0.84–1.01

0.09

Stomach

0.74

0.68–0.81

< 0.01

0.75

0.70–0.81

< 0.01

Colorectal

0.28

0.27–0.30

< 0.01

0.32

0.31–0.34

< 0.01

Liver

0.96

0.86–1.06

0.41

1.12

1.02–1.22

0.02

Pancreas

1.65

1.55–1.76

< 0.01

1.64

1.55–1.73

< 0.01

Larynx

0.24

0.19–0.29

< 0.01

0.28

0.23–0.32

< 0.01

Cervix

0.22

0.18–0.27

< 0.01

0.27

0.23–0.32

< 0.01

Kidney

0.26

0.23–0.29

< 0.01

0.33

0.30–0.36

< 0.01

Bladder

0.29

0.26–0.32

< 0.01

0.36

0.34–0.39

< 0.01

AML

1.08

0.94–1.25

0.29

1.30

1.16–1.46

< 0.01