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Table 2 Virological results of the obsessive–compulsive disorder group

From: Word recognition memory and serum levels of Borna disease virus specific circulating immune complexes in obsessive–compulsive disorder

H-group

Pat. No

CICs-Ext. (1:20)

pAG-Ext

(1:2)

Ab-Ext

(1:100)

Comment

 

1

187

56

44

 
 

2

280

70

157

 
 

3

445

9

305

 
 

4

179

25

157

 
 

5

230

11

57

 
 

6

1068

542

378

 
 

7

678

104

135

 
 

8

399

47

69

 
 

Mean ± SD

433.25 ± 305.70

108 ± 178.22

185 ± 117

 

L-group

Pat. No

CICs-Ext

pAG-Ext

Ab-Ext

Commenta

 

9

66

34

79

negative

 

10

52

72

57

negative

 

11

154

7

84

 
 

12

58

4

71

negative

 

13

137

45

181

 
 

14

96

48

198

 
 

15

164

51

60

 
 

16

162

45

54

 
 

Mean ± SD

111.13 ± 48.51

38.25 ± 22.85

90.5 ± 63.99

 

H- + L-group

Mean ± SD

272.2 ± 269

77.5 ± 131.1

137.7 ± 103.3

 
  1. Abbreviations: Ext Extinction values at 405 nm, CICs BoDV-1-specific circulating immune complexes in blood plasma, specific for BoDV-1 antigens p40/p24, pAG antigens (p40/p24) in citrated blood plasma, Ab Antibodies. The values of CICs, pAG and Ab are given as extinction at 405 nm × 1000, measured by enzyme immune assays (EIAs) in the starting dilution in brackets for each test (see Methods)
  2. The cut off value of each test is ≥ 100. Results < 100 are regarded negative
  3. H-group = patients with high CICs; L-group = patients with low CICs
  4. aComment: Patients 9, 10 and 12 were negative at the time of initial sampling (week 0) shown here but developed CICs on week 2, lasting to week 6 up to week 16 (see follow-up data, Table 3)